Background Several new atypical antipsychotics have become available for use, but
knowledge about their pharmacology may not be widespread. Objective This review aims to …

OBJECTIVE: Studies of laboratory animals have shown that administration of
antidepressants of all pharmacological classes produces changes in dopamine transporter …

Current guidelines for the treatment of bipolar type II (BP II) major depressive episode (MDE)
recommend using either mood stabilizer monotherapy or the combination of a mood …

The Food and Drug Administration set the standards for studying drug-drug interactions
(DDIs) in the US by drafting sets of guidelines for the industry. The 2006 guidelines 1 …

Major depression is related to dysfunction of the GABAergic pathway. Interestingly, the
antidepressant fluoxetine modifies GABAergic neurotransmission in human and animal …

Introduction: The treatment of depressive episodes in bipolar disorder (BD) remains a
challenge for clinicians and is a hot topic in current psychiatric practice. In the present …

Serotonin syndrome (SS) is a relatively rare but potentially life-threatening condition caused
by agents affecting serotonin (5-Hydroxytryptamine; 5-HT) metabolism or acting as direct 5 …

Personalized prescription is described even in lay journals but there has been no attempt to
propose personalizing dosing for any specific psychiatric drug. Any attempt to develop …