During the past 2 decades, results of both basic science and clinical studies have changed
the physicians' views about adipocyte pathophysiology. Since leptin was discovered in …

Patients with end-stage kidney disease (ESKD) on maintenance hemodialysis are subject to
a high burden of inflammation and cardiovascular disease, driven at least in part by …

Basic science studies have shown beneficial effects of adiponectin on glucose homeostasis,
chronic low-grade inflammation, apoptosis, oxidative stress, and atherosclerotic processes …

Adiponectin is the adipokine associated with insulin sensitization, reducing liver
gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is …

Obesity is a disease which leads to the development of many other disorders. Excessive
accumulation of lipids in adipose tissue (AT) leads to metabolic changes, including …

High-fat diet (HFD) and overnutrition are important starting factors that may alter intestinal
microbiota, lipid metabolism, and systemic inflammation. However, there were few studies …

Inflammation may be associated with mortality in dialysis patients. This study aims to
summarize the prognostic value of two common inflammatory markers, C-reactive protein …

Adiponectin is an adipocyte-specific cytokine that has a protective role in the development of
cardiovascular morbidities. As chronic kidney disease progresses, adiponectin levels …

Chronic kidney disease (CKD) is commonly associated with a high burden of comorbidities
and poor clinical outcomes. Malnutrition–inflammation–atherosclerosis syndrome is …

Background Insulin resistance (IR) is highly prevalent in chronic hemodialysis (CHD)
patients and is associated with poor cardiovascular outcomes. Hyperinsulinemic euglycemic …