Development of copper nanoclusters for in vitro and in vivo theranostic applications
Theranostics refers to the incorporation of therapeutic and diagnostic functions into one
material system. An important class of nanomaterials exploited for theranostics is metal …
material system. An important class of nanomaterials exploited for theranostics is metal …
Polymeric modification and its implication in drug delivery: poly-ε-caprolactone (PCL) as a model polymer
TK Dash, VB Konkimalla - Molecular pharmaceutics, 2012 - ACS Publications
Biodegradable polymers provided the opportunity to explore beyond conventional drug
delivery and turned out to be the focus of current drug delivery. In spite of availability of …
delivery and turned out to be the focus of current drug delivery. In spite of availability of …
Self-assembled biodegradable amphiphilic PEG–PCL–lPEI triblock copolymers at the borderline between micelles and nanoparticles designed for drug and gene …
TK Endres, M Beck-Broichsitter, O Samsonova… - Biomaterials, 2011 - Elsevier
Amphiphilic PEG–PCL–PEI triblock copolymers self-assemble into nano-scaled, positively
charged, multifunctional carriers, suitable for drug and gene delivery. A set of block …
charged, multifunctional carriers, suitable for drug and gene delivery. A set of block …
Composite liposome-PEI/nucleic acid lipopolyplexes for safe and efficient gene delivery and gene knockdown
Cytotoxicity is a major drawback impeding the therapeutic use of gene delivery and gene
down-regulation vehicles. Apart from cytotoxicity, rapid degradation and low cellular uptake …
down-regulation vehicles. Apart from cytotoxicity, rapid degradation and low cellular uptake …
Polyethyleneimine-based nanocarriers for gene delivery
X Wang, D Niu, C Hu, P Li - Current Pharmaceutical Design, 2015 - ingentaconnect.com
There is a tremendous progress in the design and synthesis of nano-scaled, non-viral
carriers in the previous two decades. The nanodelivery systems can significantly improve …
carriers in the previous two decades. The nanodelivery systems can significantly improve …
T‐cell targeted pulmonary siRNA delivery for the treatment of asthma
TWM Keil, D Baldassi, OM Merkel - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Despite the large number of drugs available for the treatment of asthma, in 5–10% of the
patients this disease is not well controlled. While most treatments palliate symptoms, those …
patients this disease is not well controlled. While most treatments palliate symptoms, those …
Folate receptor targeted delivery of siRNA and paclitaxel to ovarian cancer cells via folate conjugated triblock copolymer to overcome TLR4 driven chemotherapy …
This paper focuses on the ability of a folate-decorated triblock copolymer to deliver a
targeted dose of siRNA in order to overcome chemotherapy resistance which can commonly …
targeted dose of siRNA in order to overcome chemotherapy resistance which can commonly …
Positively charged micelles based on a triblock copolymer demonstrate enhanced corneal penetration
J Li, Z Li, T Zhou, J Zhang, H Xia, H Li, J He… - International journal …, 2015 - Taylor & Francis
Purpose The cornea is a main barrier to drug penetration after topical application. The aim of
this study was to evaluate the abilities of micelles generated from a positively charged …
this study was to evaluate the abilities of micelles generated from a positively charged …
Impact of Crystalline and Amorphous Matrices on Successful Spray Drying of siRNA Polyplexes for Inhalation of Nano‐in‐Microparticles
TWM Keil, C Zimmermann, D Baldassi… - Advanced …, 2021 - Wiley Online Library
To develop stable and inhalable dry powder formulations with long shelf life, polyplexes
consisting of siRNA and a polyethylenimine (PEI)‐based block copolymer in presence of …
consisting of siRNA and a polyethylenimine (PEI)‐based block copolymer in presence of …
Branched aliphatic polyesters by ring-opening (co) polymerization
M Bednarek - Progress in Polymer Science, 2016 - Elsevier
The rapid development of biodegradable and biocompatible materials for biomedical
applications is reflected in the search for new methods for aliphatic polyester modification …
applications is reflected in the search for new methods for aliphatic polyester modification …