The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
[HTML][HTML] Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system
B Zong, F Yu, X Zhang, Y Pang, W Zhao, P Sun… - Ageing Research …, 2023 - Elsevier
Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …
significant amount of research conducted to explore its regulatory role in the physiology and …
[HTML][HTML] Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology
P Kukanja, CM Langseth, LAR Rodríguez-Kirby… - Cell, 2024 - cell.com
Multiple sclerosis (MS) is a neurological disease characterized by multifocal lesions and
smoldering pathology. Although single-cell analyses provided insights into cytopathology …
smoldering pathology. Although single-cell analyses provided insights into cytopathology …
Mechanisms underlying the beneficial effects of physical exercise on multiple sclerosis: focus on immune cells
B Zong, F Yu, X Zhang, W Zhao, S Li, L Li - Frontiers in immunology, 2023 - frontiersin.org
Multiple sclerosis (MS) is a prevalent neuroimmunological illness that leads to neurological
disability in young adults. Although the etiology of MS is heterogeneous, it is well …
disability in young adults. Although the etiology of MS is heterogeneous, it is well …
CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis
J Beliën, S Swinnen, R D'hondt, LV de Juan… - Nature …, 2024 - nature.com
Multiple sclerosis (MS) is characterized by heterogeneity in disease course and prediction of
long-term outcome remains a major challenge. Here, we investigate five myeloid markers …
long-term outcome remains a major challenge. Here, we investigate five myeloid markers …
Exploring the clinical transition of engineered exosomes designed for intracellular delivery of therapeutic proteins
M Kim, H Choi, DJ Jang, HJ Kim, Y Sub… - Stem Cells …, 2024 - academic.oup.com
Extracellular vesicles, particularly exosomes, have emerged as promising drug delivery
systems owing to their unique advantages, such as biocompatibility, immune tolerability, and …
systems owing to their unique advantages, such as biocompatibility, immune tolerability, and …
The role of biogenic amines in the modulation of monocytes in autoimmune neuroinflammation.
O Belousova, A Lopatina, U Kuzmina… - Multiple Sclerosis and …, 2023 - Elsevier
Multiple sclerosis (MS) is inflammatory demyelinating and neurodegenerative disease of the
central nervous system (CNS) with autoimmune mechanism of development. The study of …
central nervous system (CNS) with autoimmune mechanism of development. The study of …
Exploring potential developmental origins of common neurodegenerative disorders
JP Catlin, CE Schaner Tooley - Biochemical Society …, 2024 - portlandpress.com
In the United States, it is now estimated that 6.7 million people over the age of 65 are
afflicted by Alzheimer's disease (AD), over 1 million people are living with Parkinson's …
afflicted by Alzheimer's disease (AD), over 1 million people are living with Parkinson's …
Single cell-resolution in situ sequencing elucidates spatial dynamics of multiple sclerosis lesion and disease evolution
CM Langseth, P Kukanja, LA Rubio Rodríguez-Kirby… - bioRxiv, 2023 - biorxiv.org
Multiple sclerosis (MS) is a neurological disease characterised by multifocal lesions and
smouldering pathology. While single-cell analyses have provided insights into …
smouldering pathology. While single-cell analyses have provided insights into …
Brain-Immune interactions: Implication for Cognitive impairments in Alzheimer's Disease and autoimmune disorders
Progressive memory loss and cognitive dysfunction, encompassing deficits in learning,
memory, problem-solving, spatial reasoning, verbal expression are characteristics of …
memory, problem-solving, spatial reasoning, verbal expression are characteristics of …