The Na+-Cl− cotransporter (NCC; SLC12A3) is a highly regulated integral membrane
protein that is known to exist as three splice variants in primates. Its primary role in the …

INTRODUCTION—The global prevalence of hypertension is high, and among nonpregnant
adults in the United States, treatment of hypertension is the most common reason for office …

Objective Impairment of circadian blood pressure (BP) patterns has been associated with
cardiovascular risks and events in individuals with hypertension and in general populations …

Abstract Purpose of Review Blood pressure (BP) fluctuations outside of clinic are
increasingly recognized for their role in the development of cardiovascular disease …

Nocturnal hypertension is highly prevalent among Chinese and Asian populations, which is
mainly attributed to high salt intake and high salt sensitivity. Nocturnal hypertension …

Introduction BedMed-Frail explores risks and benefits of switching antihypertensives from
morning to bedtime in a frail population at greater risk of hypotensive adverse effects …

Stroke remains one of the leading causes of mortality and long-term and permanent
disability worldwide despite technological innovations and developments in …

A comprehensive approach to hypertension requires out-of-office determinations by home or
ambulatory monitoring. The 4 phenotypes comparing office and out-of-office pressures in …

Introduction Clinical hypertension trials typically rely on homeostatic principles, including
single time-of-day office blood pressure (BP) measurements (OBPM), rather than circadian …

Should blood pressure (BP) medications be taken in the morning or in the evening? The
TIME study results were presented at the ESC congress 2022 and published not too long …