Processes similar to endochondral or intramembranous bone formation occur in the
vascular wall. Bone and cartilage tissue as well as osteoblast-and chondrocyte-like cells are …

The use of extracellular vesicles (EVs) as a potential therapy is currently explored for
different disease areas. When it comes to the treatment of joint diseases this approach is still …

Substantial progress has been made in identifying the extracellular signalling pathways that
regulate neural stem and precursor cell biology in the central nervous system (CNS). The …

Extracellular vesicles (EVs) are nanoparticles that include exosomes, microvesicles, and
apoptotic bodies; they interact with target cell surface receptors and transport contents …

Matrix vesicles (MVs) are membrane organelles found in the extracellular matrix of calcifying
cells, which contain matrix processing enzymes and regulate the extracellular environment …

This study investigated whether osteocalcin (OCN) is present in osteoblast precursors and
its relationship with initial phases of alveolar process formation. Samples of maxillae of 16 …

Transplanting mesenchymal stem cells (MSCs) has been widely perceived as an ideal
treatment for bone repair and regeneration, owing to their differential potential. However …

The bone microenvironment (BME) is the main hub of all skeletal related pathological events
in osteosarcoma leading to tumor induced bone destruction, and decreasing overall bone …

Extracellular vesicles (EVs) are phospholipid membrane-enclosed entities containing
specific proteins, RNA, miRNA, and lncRNA. EVs are released by various cells and play a …

A challenge in regenerative medicine is creating the three-dimensional organic and
inorganic in vitro microenvironment of bone, which would allow the study of musculoskeletal …