Tranexamic acid evidence and controversies: an illustrated review
N Relke, NLJ Chornenki… - Research and practice in …, 2021 - Wiley Online Library
Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or
prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding …
prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding …
[HTML][HTML] Tranexamic acid for the prevention of blood loss after cesarean section: an updated systematic review and meta-analysis of randomized controlled trials
OBJECTIVE Tranexamic acid is a cost-effective intervention for the prevention of postpartum
hemorrhage among women who undergo cesarean delivery, but the evidence to support its …
hemorrhage among women who undergo cesarean delivery, but the evidence to support its …
Optimal use of intravenous tranexamic acid for hemorrhage prevention in pregnant women
Background Every 2 minutes, there is a pregnancy-related death worldwide, with one-third
caused by severe postpartum hemorrhage. Although international trials demonstrated the …
caused by severe postpartum hemorrhage. Although international trials demonstrated the …
The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries
R Picetti, L Miller, H Shakur-Still, T Pepple… - BMC Pregnancy and …, 2020 - Springer
Background Post-partum haemorrhage (PPH) is a leading cause of maternal death
worldwide. The WOMAN trial assessed the effects of tranexamic acid (TXA) on death and …
worldwide. The WOMAN trial assessed the effects of tranexamic acid (TXA) on death and …
Tranexamic acid and obstetric hemorrhage: give empirically or selectively?
A Shander, M Javidroozi, L Sentilhes - International Journal of Obstetric …, 2021 - Elsevier
Antifibrinolytic agents such as tranexamic acid (TXA) inhibit the fibrinolytic pathway and
protect blood clots from being degraded, thereby promoting hemostasis. They have been …
protect blood clots from being degraded, thereby promoting hemostasis. They have been …
[HTML][HTML] Tranexamic acid for post-partum haemorrhage: What, who and when
Tranexamic acid reduces bleeding by inhibiting the breakdown of blood clots. It is cost-
effective and heat-stable with a long shelf life. In the WOMAN trial, tranexamic acid reduced …
effective and heat-stable with a long shelf life. In the WOMAN trial, tranexamic acid reduced …
Tranexamic acid for postpartum hemorrhage treatment in low-resource settings: A rapid scoping review
NT Tran, S Bar-Zeev, C Schulte-Hillen… - International Journal of …, 2022 - mdpi.com
Tranexamic acid (TXA) effectively reduces bleeding in women with postpartum hemorrhage
(PPH) in hospital settings. To guide policies and practices, this rapid scoping review …
(PPH) in hospital settings. To guide policies and practices, this rapid scoping review …
The role of tranexamic acid in the management of postpartum haemorrhage
AS Bouthors, S Gilliot, L Sentilhes, B Hennart… - Best Practice & …, 2022 - Elsevier
In the last decades, tranexamic acid (TXA) has emerged as an essential tool in blood loss
management in obstetrics. TXA prophylaxis for postpartum haemorrhage (PPH) has been …
management in obstetrics. TXA prophylaxis for postpartum haemorrhage (PPH) has been …
Improving development of drug treatments for pregnant women and the fetus
AL David, H Ahmadzia, R Ashcroft… - … innovation & regulatory …, 2022 - Springer
The exclusion of pregnant populations, women of reproductive age, and the fetus from
clinical trials of therapeutics is a major global public health issue. It is also a problem of …
clinical trials of therapeutics is a major global public health issue. It is also a problem of …
Emergencies in obstetric anaesthesia: a narrative review
CH Prior, CEG Burlinson, A Chau - Anaesthesia, 2022 - Wiley Online Library
We conducted a narrative review in six areas of obstetric emergencies: category‐1
caesarean section; difficult and failed airway; massive obstetric haemorrhage; hypertensive …
caesarean section; difficult and failed airway; massive obstetric haemorrhage; hypertensive …