Radiotherapy treatment for lung cancer: Current status and future directions

SK Vinod, E Hau - Respirology, 2020 - Wiley Online Library
Radiotherapy is an important modality used for the treatment of lung cancer. Seventy‐seven
percent of all patients with lung cancer have an evidence‐based indication for radiotherapy …

Radiation and systemic therapy for limited-stage small-cell lung cancer

JA Bogart, SN Waqar, MD Mix - Journal of Clinical Oncology, 2022 - ascopubs.org
Progress in the overall treatment of small-cell lung cancer (SCLC) has moved at a slower
pace than non–small-cell lung cancer. In fact, the standard treatment regimen for limited …

Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

AMC Dingemans, M Früh, A Ardizzoni… - Annals of …, 2021 - annalsofoncology.org
Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer. Although SCLC is
characterised by rapid responses to chemotherapy (ChT) and sensitivity to radiotherapy …

Radiation therapy for small cell lung cancer: an ASTRO clinical practice guideline

CB Simone II, JA Bogart, AR Cabrera, ME Daly… - Practical radiation …, 2020 - Elsevier
Purpose Several sentinel phase III randomized trials have recently been published
challenging traditional radiation therapy (RT) practices for small cell lung cancer (SCLC) …

Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised …

C Faivre-Finn, M Snee, L Ashcroft, W Appel… - The Lancet …, 2017 - thelancet.com
Background Concurrent chemoradiotherapy is the standard of care in limited-stage small-
cell lung cancer, but the optimal radiotherapy schedule and dose remains controversial. The …

ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer

U Nestle, D De Ruysscher, U Ricardi, X Geets… - Radiotherapy and …, 2018 - Elsevier
Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small
cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to …

Survival changes in patients with small cell lung cancer and disparities between different sexes, socioeconomic statuses and ages

S Wang, J Tang, T Sun, X Zheng, J Li, H Sun, X Zhou… - Scientific reports, 2017 - nature.com
Small cell lung cancer (SCLC), as a proportion, makes up only 15–17% of lung cancer
cases. The development of treatments for SCLC has remained stagnant for decades, and …

Recent developments in the treatment of small cell lung cancer

BI Hiddinga, J Raskin, A Janssens… - European …, 2021 - Eur Respiratory Soc
Small cell lung cancer (SCLC) comprises about 15% of all lung cancers. It is an aggressive
disease, with early metastasis and a poor prognosis. Until recently, SCLC treatment …

A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers

B Zhang, K Ramkumar, RJ Cardnell, CM Gay… - British journal of …, 2021 - nature.com
DNA-damaging agents exploit increased genomic instability, a hallmark of cancer. Recently,
inhibitors targeting the DNA damage response (DDR) pathways, such as PARP inhibitors …

SEOM clinical guidelines for the treatment of small-cell lung cancer (SCLC)(2019)

M Dómine, T Moran, D Isla, JL Martí, I Sullivan… - Clinical and …, 2020 - Springer
Small-cell lung cancer (SCLC) accounts for 15% of lung cancers. Only one-third of patients
are diagnosed at limited stage. The median survival remains to be around 15–20 months …