Malignant gliomas are the most common and deadly type of central nervous system tumors.
Despite some advances in treatment, the mean survival time remains only about 1.25 years …

In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …

Simple Summary Glioblastoma is the most common and malignant primary brain tumor.
Despite intensive research for new treatments, the survival of patients has not significantly …

Glioblastoma (GBM) is the most lethal primary brain tumor and has a complex molecular
profile. Hypoxia plays a critical role during tumor progression and in the tumor …

Simple Summary Despite a substantial increase in publications in recent years, liquid biopsy
from blood, cerebrospinal fluid (CSF), and other body fluids is usually not routinely used in …

Cancer is designated as one of the principal causes of mortality universally. Among different
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …

Survival for glioma patients has shown minimal improvement over the past 20 years. The
ability to detect and monitor gliomas relies primarily upon imaging technologies that lack …

Accurate circulating biomarkers have potential clinical applications in population screening,
tumor subclassification, monitoring tumor status, and the delivery of individualized …

Exosomes are extracellular vesicles with the diameter ranging from 50 to 100 nm and are
found in different body fluids such as blood, cerebrospinal fluid (CSF), urine and saliva. Like …

Biofluid-accessible extracellular vesicles (EVs) may represent a new means to improve the
sensitivity and specificity of detecting disease. However, current methods to isolate EVs …