Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

Mesenchymal stem cells (MSCs) have been identified in many adult tissues. MSCs can
regenerate through cell division or differentiate into adipocytes, osteoblasts and …

Objectives Circular RNAs (circRNA) expression aberration has been identified in various
human diseases. In this study, we investigated whether circRNAs could act as competing …

Osteoarthritis (OA) is a serious disease of the articular cartilage, and inflammation has been
implicated in its pathogenesis. Previously, microRNAs (miRNAs) have been proposed as …

An imbalance in gene expressional events skewing chondrocyte anabolic and catabolic
pathways toward the latter causes an aberrant turnover and loss of extracellular matrix …

Osteoarthritis (OA) is a degenerative disease of the joints and is one of the leading causes of
disability in adults. However, there are no key therapeutics for OA and medical treatment is …

Osteoarthritis (OA) is a degenerative joint disease caused by articular cartilage degradation
and joint inflammation, with considerable involvement of microRNAs and circular RNAs …

Bone formation and regeneration is a multistep complex process crucially determined by the
formation of blood vessels in the growth plate region. This is preceded by the expression of …

Osteoarthritis (OA) is characterized by degradation of articular cartilage and joint
inflammation. MicroRNAs have been proved to play an important role in the regulation of …

Osteoarthritis (OA), the most prevalent chronic and degenerative joint disease, is
characterized by articular cartilage degradation and chondrocyte injury. Increased cell …