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The insulin-like growth factors (IGFs), IGF binding proteins (IGFBPs), and the IGFBP
proteases (BP-Pr) are involved in the regulation of somatic growth and cellular proliferation …

The etiology of osteoporosis in most men without a history of alcohol abuse, hypogonadism,
or glucocorticoid excess is unknown. Several histomorphometric reports have demonstrated …

The insulin-like growth factors (IGFs), insulin-like growth factors binding proteins (IGFBPs),
and the IGFBP proteases (BP-Pr) are involved in the regulation of somatic growth and …

With the increasing worldwide prevalence of diabetes the resulting complications, their
consequences and treatment will lead to a greater social and financial burden on society …

Osteoblast-like cells secrete insulin-like growth factor (IGF) binding protein-5 (IGFBP-5),
which may act to enhance IGF-stimulated osteoblast function. We recently demonstrated that …

The insulin-like growth factors (IGFs) have diverse anabolic cellular functions, and structure
similar to that of proinsulin. The distribution of ICFs and their receptors in a wide variety of …

Diabetes affects over 25 million people and is characterized by hyperglycemia resulting from
a lack of insulin or reduced insulin sensitivity. A serious complication of diabetes is the …

Growth in teleosts is controlled in large part by the activities of the growth hormone
(Gh)/insulin-like growth factor (Igf) system. In this study, we initially identified igf-binding …

The growth hormone (Gh)/insulin-like growth-factor (Igf)/Igf binding protein (Igfbp) system
regulates growth and osmoregulation in salmonid fishes, but how this system interacts with …