Immune checkpoint blockade targeting the programmed death-1 (PD-1) pathway has shown
efficacy in several types of cancers including mismatch-repair-deficient colorectal …

Dexamethasone provides benefits in patients with coronavirus disease 2019 (COVID-19),
although data regarding immunological profiles and viral clearance are limited. This study …

Objective The Systemic Synuclein Sampling Study (S4) measured α-synuclein in multiple
tissues and biofluids within the same patients with Parkinson disease (PD) vs healthy …

Purpose In studies of diffuse large B-cell lymphoma, positron emission tomography with
[18F] fluorodeoxyglucose (FDG-PET) performed after two to four cycles of chemotherapy has …

Background The tumor microenvironment is important for the behavior of cancer. We
assessed the distribution and biological significance of FOXP3+ regulatory T-cells (Treg) in …

In recent decades, global warming has contributed to an increase in the number and
intensity of wildfires destroying millions hectares of forest areas and causing many …

Preeclampsia is a pregnancy-specific syndrome that causes substantial maternal and fetal
morbidity and mortality. The etiology is incompletely understood, and there is no clinically …

Abstract Estrogen receptor–negative (ER−) breast cancers have limited treatment options
and are associated with earlier relapses. Because glucocorticoid receptor (GR) signaling …

The predictive validity of violence risk assessments can be divided into two components:
calibration and discrimination. The most common performance indicator used to measure …

The scored Patient-Generated Subjective Global Assessment tool (PG-SGA), regarded as
the most appropriate means of identifying malnutrition in cancer patients, is often …