Cardiac dysfunction has an increased prevalence in diseases complicated by liver cirrhosis
such as primary biliary cholangitis and primary sclerosing cholangitis. This observation has …

Cirrhotic cardiomyopathy historically has been confused as alcoholic cardiomyopathy. The
key points for diagnosis of cirrhotic cardiomyopathy have been well explained, however this …

Patients with advanced liver cirrhosis may develop a clinical syndrome characterized by a
blunted contractile responsiveness to stress and/or altered diastolic relaxation, called …

Cirrhotic cardiomyopathy is a cardiac condition observed in patients with cirrhotic regardless
of the etiologies. It is characterized by the impaired systolic response to physical stress …

Cardiac dysfunction in patients with liver cirrhosis is strongly associated with increased
serum bile acid concentrations. Here we show that excess bile acids decrease fatty acid …

Communication between organs participates in most physiological and pathological events.
Owing to the importance of precise coordination among the liver and virtually all organs in …

Background: Cirrhotic cardiomyopathy is described as latent cardiac failure. However, it
remains to be investigated whether the myocardial dysfunction is present even at rest. Aims …

In recent years, a wealth of studies has identified various molecular species released by
cardiac muscle under physiological and pathological conditions that exert local paracrine …

Background Cardiac involvement in liver cirrhosis in the absence of underlying cardiac
disease is termed cirrhotic cardiomyopathy. The pathophysiology of this condition is still …

Background and Aims Hepatic cardiomyopathy, a special type of heart failure, develops in
up to 50% of patients with cirrhosis and is a major determinant of survival. However, there is …