Gel entrapment and micro-encapsulation: Methods, applications and engineering principles

RG Willaert, GV Baron - Reviews in chemical engineering, 1996 - degruyter.com
Methods, modelling and applications of gel immobilisation and micro-encapsulation of living
cells are reviewed. These two methods are most frequently used as they allow for excellent …

Plant cell cultures: chemical factories of secondary metabolites

SR Rao, GA Ravishankar - Biotechnology advances, 2002 - Elsevier
This review deals with the production of high-value secondary metabolites including
pharmaceuticals and food additives through plant cell cultures, shoot cultures, root cultures …

Plant biotechnology for the production of alkaloids: present status and prospects

R Verpoorte, R van der Heijden, WM van Gulik… - The alkaloids: chemistry …, 1991 - Elsevier
Publisher Summary This chapter reviews the state of the art of plant cell biotechnology for
the production of commercially important alkaloids. Plant cell and tissue culture methods …

Enhanced shikonin production from Lithospermum erythrorhizon by in situ extraction and calcium alginate immobilization

DJ Kim, HN Chang - Biotechnology and Bioengineering, 1990 - Wiley Online Library
Plant cell cultures of Lithospermum erythrorhizon were carried out to produce shikonin by in
situ extraction and cell immobilization in calcium alginate bead in shake flask cultures. In situ …

The scale-up of plant cell culture: Engineering considerations

RA Taticek, M Moo-Young, RL Legge - Plant Cell, Tissue and Organ …, 1991 - Springer
The enormous versatility of plants has continued to provide the impetus for the development
of plant tissue culture as a commercial production strategy for secondary metabolites …

Taxol (paclitaxel) production using free and immobilized cells of Taxus cuspidata

M Seki, C Ohzora, M Takeda… - Biotechnology and …, 1997 - Wiley Online Library
The production characteristics for Taxol (paclitaxel) using free and immobilized cells of
Taxus cuspidata were investigated in a perfusion culture bioreactor. Although the cell growth …

Design of reactors for plant cells and organs

PM Doran - Bioprocess design and control, 2005 - Springer
To be economically feasible, production of most secondary metabolites by plant-cell culture
requires high cell densities. In standard reactor configurations such as stirred-tank and airlift …

Modeling and control for anaerobic wastewater treatment

E Heinzle, IJ Dunn, GB Ryhiner - Bioprocess Design and Control, 1993 - Springer
The recent literature on the modeling and control of anaerobic wastewater treatment
processes is reviewed. An example from the author's personal work is used to describe how …

The effect of the aggregate size on the production of ajmalicine and tryptamine in Catharanthus roseus suspension culture

M Keßler, HJG ten Hoopen, S Furusaki - Enzyme and microbial technology, 1999 - Elsevier
A suspension culture of Catharanthus roseus grown in shake flasks was placed in a
bioreactor containing production medium. After 6, 9, and 12 days, samples were taken and …

Biotransformation of codeine to morphine in freely suspended cells and immobilized cultures of Spirulina platensis

S Ramachandra Rao, U Tripathi… - World Journal of …, 1999 - Springer
Both freely suspended cells and immobilized cultures of Spirulina platensis, a blue-green
alga, biotransformed exogenously fed codeine, an opium alkaloid, to morphine. The external …