Converting “cold” to “hot”: epigenetics strategies to improve immune therapy effect by regulating tumor‐associated immune suppressive cells
Y Tang, G Cui, H Liu, Y Han, C Cai… - Cancer …, 2024 - Wiley Online Library
Significant developments in cancer treatment have been made since the advent of immune
therapies. However, there are still some patients with malignant tumors who do not benefit …
therapies. However, there are still some patients with malignant tumors who do not benefit …
Metformin-induced reduction of CCR8 enhances the anti-tumor immune response of PD-1 immunotherapy in glioblastoma
Y Li, B Liu, Y Cao, L Cai, Y Zhou, W Yang… - European Journal of …, 2024 - Elsevier
Immunotherapy strategies targeting the programmed cell death 1 (PD-1) in clinical
treatments have shown limited success in controlling glioblastoma malignancies. Metformin …
treatments have shown limited success in controlling glioblastoma malignancies. Metformin …
The Clinical Association Between the Inflammation-Nutritional Condition and Prognosis of Locally Advanced Intrahepatic Cholangiocarcinoma After R0 Resection …
G Huang, P Xi, Z Yao, C Zhao, X Li… - Journal of Inflammation …, 2024 - Taylor & Francis
Background Intrahepatic cholangiocarcinoma (ICC) correlates with poor outcomes,
necessitating the identification of prognostic factors from an inflammation-nutritional …
necessitating the identification of prognostic factors from an inflammation-nutritional …
A Therapeutic Vaccine Targeting Rat BORIS (CTCFL) for the Treatment of Rat Breast Cancer Tumors
D Loukinov, AL Anderson, M Mkrtichyan… - International journal of …, 2023 - mdpi.com
Cancer testis antigens are ideal for tumor immunotherapy due to their testis-restricted
expression. We previously showed that an immunotherapeutic vaccine targeting the germ …
expression. We previously showed that an immunotherapeutic vaccine targeting the germ …
Neoadjuvant therapy with chemotherapy and immune checkpoint inhibitor for laryngeal function preservation in locally advanced hypopharyngeal cancer
SG Wu, RJ Wang, Y Zhou, XY Luo - Frontiers in Immunology, 2024 - frontiersin.org
Purpose To evaluate the efficacy and laryngeal function preservation of neoadjuvant
treatment with chemotherapy and immune checkpoint inhibitor for locally advanced …
treatment with chemotherapy and immune checkpoint inhibitor for locally advanced …
Detailed Profiling of the Tumor Microenvironment in Ethnic Breast Cancer, Using Tissue Microarrays and Multiplex Immunofluorescence
M Zaakouk, A Longworth, K Hunter, S Jiman… - International Journal of …, 2024 - mdpi.com
Breast cancer poses a global health challenge, yet the influence of ethnicity on the tumor
microenvironment (TME) remains understudied. In this investigation, we examined immune …
microenvironment (TME) remains understudied. In this investigation, we examined immune …
Regulatory T cells as crucial trigger and potential target for hyperprogressive disease subsequent to PD-1/PD-L1 blockade for cancer treatment
Z Ren, K Yang, L Zhu, D Yin, Y Zhou - International Immunopharmacology, 2024 - Elsevier
Abstract PD-1/PD-L1 blockade therapy has brought great success to cancer treatment.
Nevertheless, limited beneficiary populations and even hyperprogressive disease (HPD) …
Nevertheless, limited beneficiary populations and even hyperprogressive disease (HPD) …
Tumor-associated macrophages affect the treatment of lung cancer
Z Yu, J Zou, F Xu - Heliyon, 2024 - cell.com
As one of the most common malignant tumors in the world, lung cancer has limited benefits
for patients despite its diverse treatment methods due to factors such as personalized …
for patients despite its diverse treatment methods due to factors such as personalized …
TRIM5 as a promising diagnostic biomarker of hepatocellular carcinoma: integrated analysis and experimental validation
H Liu, Y Tang, J Zhang, G Wu, Q Peng, C Chen… - Functional & Integrative …, 2024 - Springer
The TRIM family is associated with the membrane, and its involvement in the progression,
growth, and development of various cancer types has been researched extensively …
growth, and development of various cancer types has been researched extensively …
Enhancement of Tumor Antigen-specific T-cell Responses by Immune Checkpoint Blockade in Human Papillomavirus-related Head and Neck Squamous Cell …
K Chikamatsu, S Ida, K Masuda, M Horikawa… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: Human papillomavirus (HPV)-positive head and neck squamous cell
carcinoma (HNSCC) is clinically and immunologically distinct from HPV-negative HNSCC …
carcinoma (HNSCC) is clinically and immunologically distinct from HPV-negative HNSCC …