Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating
research to improve diagnostics, and to discover and test novel preventive and curative …

Bone morphogenetic proteins (BMPs) are dimeric transforming growth factor ß (TGFß) family
cytokines that were first described in bone and cartilage formation but have since been …

Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains
difficult and AF-related complications cause unacceptable morbidity and mortality even on …

Aims Biomarkers specifically related to atrial tissue may increase the understanding of the
pathophysiology of atrial fibrillation (AF) and further improve risk prediction in this setting …

Bone morphogenetic proteins (BMPs) are secretory proteins belonging to the transforming
growth factor-β (TGF-β) superfamily. These proteins play important roles in embryogenesis …

Background: Electrical remodeling in human persistent atrial fibrillation is believed to result
from rapid electrical activation of the atria, but underlying genetic causes may contribute …

Biomarkers may help to improve our knowledge about the complex pathophysiology of atrial
fibrillation (AF). In this study we sought to identify significant changes in biomarkers and …

Background Novel circulating biomarkers may help in understanding the underlying
mechanisms of atrial fibrillation (AF), a challenge for AF management and prevention of …

Background Patients with atrial fibrillation (AF) face an increased risk of death and major
adverse cardiovascular events (MACE). We aimed to assess the predictive value of the …

Aims Recent trial data demonstrate beneficial effects of active rhythm management in
patients with atrial fibrillation (AF) and support the concept that a low arrhythmia burden is …