Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

An endothelium‐derived hyperpolarizing factor (EDHF) that is distinct from nitric oxide (NO)
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …

Intercellular communication in many organs is maintained via intercellular gap junction
channels composed of connexins, a large protein family with a number of isoforms. This gap …

Gap junctions are common features in the vasculature, long thought to provide a pathway for
cell-cell signaling. Emerging understanding of the gap-junctional proteins (connexins) and …

Modulation of vascular cell calcium is critical for the control of vascular tone, blood flow and
pressure. 2. Specialized microdomain signalling sites associated with calcium modulation …

Gap junction channels provide the basis for intercellular communication and play an
important physiological role in the cardiovascular system for maintenance of the normal …

Although an endothelium-derived hyperpolarizing factor (EDHF) has often been
hypothesized to underpin vascular relaxations that are independent of nitric oxide (NO) and …

1. PREFACE This thesis is based on the work carried in the Vascular Smooth Muscle group
at the Institute of Physiology and Biophysics, Aarhus University. This thesis is focused on a …

Arterial smooth muscle Na+/Ca2+ exchanger-1 (SM-NCX1) promotes vasoconstriction or
vasodilation by mediating, respectively, Ca2+ influx or efflux. In vivo, SM-NCX1 mediates net …

Российский кардиологический журнал № 1 (69)/2008 ном уров нях. Од на ко эн до те
лий за ви си мая ва зо дила та ция не яв ля ет ся функ ци ей; это толь ко по ло вина …