[HTML][HTML] Progression in translational research on spinal cord injury based on microenvironment imbalance
B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …
and imposes a considerable burden on patients, families, and society. Repair of the injured …
[HTML][HTML] Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - … and Targeted Therapy, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Microglia play an active role in obesity-associated cognitive decline
Obesity affects> 600 million people worldwide, a staggering number that appears to be on
the rise. One of the lesser known consequences of obesity is its deleterious effects on …
the rise. One of the lesser known consequences of obesity is its deleterious effects on …
[HTML][HTML] Immune response following traumatic spinal cord injury: Pathophysiology and therapies
RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
[HTML][HTML] Recent trends in the development of hydrogel therapeutics for the treatment of central nervous system disorders
Q Li, X Shao, X Dai, Q Guo, B Yuan, Y Liu… - NPG Asia …, 2022 - nature.com
The central nervous system (CNS) controls the acquisition and processing of peripheral
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …
Is graphene shortening the path toward spinal cord regeneration?
Along with the development of the next generation of biomedical platforms, the inclusion of
graphene-based materials (GBMs) into therapeutics for spinal cord injury (SCI) has potential …
graphene-based materials (GBMs) into therapeutics for spinal cord injury (SCI) has potential …
Co-delivery of minocycline and paclitaxel from injectable hydrogel for treatment of spinal cord injury
Spinal cord injury (SCI) induces pathological and inflammatory responses that create an
inhibitory environment at the site of trauma, resulting in axonal degeneration and functional …
inhibitory environment at the site of trauma, resulting in axonal degeneration and functional …
The overlooked aspect of excitotoxicity: Glutamate‐independent excitotoxicity in traumatic brain injuries
J Tehse, C Taghibiglou - European journal of neuroscience, 2019 - Wiley Online Library
Traumatic brain injury (TBI) is a leading major cause of morbidity and mortality in youth and
individuals under 45 year age. A wide variety of cellular and molecular mechanisms have …
individuals under 45 year age. A wide variety of cellular and molecular mechanisms have …
[HTML][HTML] Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury
SF Abcouwer, S Shanmugam, A Muthusamy… - Journal of …, 2021 - Springer
Background Several retinal pathologies exhibit both inflammation and breakdown of the
inner blood-retinal barrier (iBRB) resulting in vascular permeability, suggesting that …
inner blood-retinal barrier (iBRB) resulting in vascular permeability, suggesting that …
Melatonin enhances autophagy and reduces apoptosis to promote locomotor recovery in spinal cord injury via the PI3K/AKT/mTOR signaling pathway
Y Li, Y Guo, Y Fan, H Tian, K Li, X Mei - Neurochemical research, 2019 - Springer
Spinal cord injury (SCI) leads to neuronal death resulting in central nervous system (CNS)
dysfunction; however, the pathogenesis is still poorly understood. Melatonin (MT), a …
dysfunction; however, the pathogenesis is still poorly understood. Melatonin (MT), a …