The role of nitric oxide in mice infected with Trichobilharzia regenti, the neuropathogenic schistosome

B Šmídová - 2019 - dspace.cuni.cz
Nitric oxide (NO) has been proved to reduce parasite burden in vertebrates infected with
Schistosoma, Fasciola, Brugia or Taenia. NO negatively influences parasite growth and …

Effects of Cyclosporin-A, Minocycline, and Tacrolimus (FK506) on Enhanced Behavioral and Biochemical Recovery from Spinal Cord Injury in Rats

M Ahmad, AS Alshehri - Spinal Cord Injury Therapy, 2019 - books.google.com
Spinal cord injury (SCI) results into an immediate primary injury (physical damages)
followed by secondary damages (prolonged posttraumatic inflammatory disorder) resulting …

Can minocycline become the magic pill of spinal cord protection?

JK Frogel, G Zahavi - Journal of Cardiothoracic and Vascular …, 2019 - jcvaonline.com
In this month's issue of the Journal of Cardiothoracic and Vascular Anesthesia, Drenger et
al. demonstrate the protective effects of minocycline pretreatment on the spinal cord after an …

Serotonin-Associated Pathways in Viral-and Inflammation-Mediated Disease Processes: An Evaluation of the Therapeutic Potential of 5-HT2 Receptor Agonism

D Battaglia - 2021 - search.proquest.com
HSV-1 is the leading cause of infectious blindness in the developed world. Virus-associated
diseases, including herpetic stromal keratitis (HSK) are complex interactions between viral …

Oligodendrocyte responses after spinal cord injury.

GZ Wei - 2021 - ir.library.louisville.edu
Recent studies demonstrate that neuroprotection strategies targeting the proteostasis
network and components of its effector signaling pathways improve cell survival and motor …

Bio-Cellulose Based Composite Protein Delivery System for Spinal Cord Regeneration

H Ismail - 2020 - ruor.uottawa.ca
Background: Spinal cord injury (SCI) is a devastating condition for which current treatment
strategies provide no cure. Delivery of growth factors at the injury site may stimulate …

Effect of PI3K/Akt Signaling Pathway on Proliferation, Differentiation and Functional Recovery of Endogenous Neural Stem Cells in Rats with Spinal Cord Injury

R Cheng, X Ye, C Ni, R Wang, Q Tong, P Sun… - … Functional Recovery of … - papers.ssrn.com
Background: This study was aimed to clarify the role of PI3K/Akt signaling pathway in spinal
cord injury (SCI). Methods: SCI animal models were established. BBB score was adopt to …

[PDF][PDF] Blocking the EGFR/p38/NF-κB Signal Pathway Alleviates Disruption of BSCB and Subsequent Inflammation After Spinal Cord Injury

ZW Li, JJ Zhao, SY Li, TT Cao, Y Wang, Y Guo, GJ Xi - 2021 - scholar.archive.org
Background: Epidermal growth factor receptor (EGFR) activation may play an important role
in blood spinal cord barrier (BSCB) disruption and secondary injury after SCI as it is signi …

Tetracyclines beyond the antibiotic

ML Carraro - 2019 - repositorio.ul.pt
The antibiotic effect of tetracyclines has been widely studied and demonstrated over the
years. However, tetracyclines have been reborn at the time of recovering sensibility and …

Clinical trials: pharmacological approaches to enhance neural repair and regeneration after spinal cord injury

AK Malhotra, LD Hachem, JH Badhiwala… - Neural Repair and …, 2022 - Elsevier
Spinal cord injury (SCI) is associated with significant physical and psychological morbidity
among patients and carries major economic ramifications to both individuals and health …