Generally, several mechanisms influenced the secondary injury chutes following acute
spinal cord injury (SCI). Though current SCI therapeutic approaches mostly target single …

Unconjugated bilirubin, the end product of heme catabolism and antioxidant, induced brain
damage in human neonates is a well-recognized clinical syndrome. However, the cellular …

Spinal cord injury (SCI) is traumatic central nervous system damage resulting in a motor and
sensory dysfunction that usually causes a severe and permanent paralysis. Today, the …

ABSTRACT Phosphoinositide-3 kinases and Rac GTPases play important roles in a wide
variety of cellular responses downstream of cell surface receptors. Although their activation …

脊髓损伤的治疗一直是基础和临床医学领域的研究重点. 本文介绍米诺环素治疗脊髓损伤的作用
机制, 包括抗氧化活性, 减少细胞凋亡, 抗炎作用, 选择性调节小胶质细胞的活化状态等 …

Peroxidase activity of cytochrome c stimulated by interaction of the protein with cardiolipin is
considered to be involved in the induction of mitochondrial apoptosis associated with …

Objective This randomized clinical trial (RCT) aimed to compare the neurologic outcomes of
spinal cord injury (SCI) patients treated with Minocycline plus methylprednisolone (MCMP) …

摘要背景: 骨髓间充质干细胞作为一种具有多向分化能力的成体多能干细胞,
已在多项脊髓损伤相关研究中被证实有效, 逐渐成为国内外基础及应用研究的热点 …

Background. Despite considerable interest in the search for a spinal cord injury (SCI)
therapy, there is a critical need to develop a panel of diagnostic biomarkers to determine …

Spinal cord injury (SCI) is one of the major causes of irreversible nerve injury, affecting both
sensory and motor neurons, which poses a significant physical, emotional, and economic …