Mechanisms of antifungal drug resistance

LE Cowen, D Sanglard… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

[HTML][HTML] Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options

JCO Sardi, L Scorzoni, T Bernardi… - Journal of medical …, 2013 - microbiologyresearch.org
The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …

Bacteriome and mycobiome interactions underscore microbial dysbiosis in familial Crohn's disease

G Hoarau, PK Mukherjee, C Gower-Rousseau… - MBio, 2016 - Am Soc Microbiol
Crohn's disease (CD) results from a complex interplay between host genetic factors and
endogenous microbial communities. In the current study, we used Ion Torrent sequencing to …

[HTML][HTML] Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

Antifungal resistance and new strategies to control fungal infections

P Vandeputte, S Ferrari… - International journal of …, 2012 - Wiley Online Library
Despite improvement of antifungal therapies over the last 30 years, the phenomenon of
antifungal resistance is still of major concern in clinical practice. In the last 10 years the …

The regulation of filamentous growth in yeast

PJ Cullen, GF Sprague Jr - Genetics, 2012 - academic.oup.com
Filamentous growth is a nutrient-regulated growth response that occurs in many fungal
species. In pathogens, filamentous growth is critical for host–cell attachment, invasion into …

[图书][B] Fundamentals of biofilm research

Z Lewandowski, H Beyenal - 2013 - books.google.com
The six years that have passed since the publication of the first edition have brought
significant advances in both biofilm research and biofilm engineering, which have matured …

[HTML][HTML] Potential Use of Phenolic Acids as Anti-Candida Agents: A Review

GR Teodoro, K Ellepola, CJ Seneviratne… - Frontiers in …, 2015 - frontiersin.org
There has been a sharp rise in the occurrence of Candida infections and associated
mortality over the last few years, due to the growing body of immunocompromised …

[HTML][HTML] Update on antifungal drug resistance

DS Perlin, E Shor, Y Zhao - Current clinical microbiology reports, 2015 - Springer
Invasive fungal infections remain a major source of global morbidity and mortality, especially
among patients with underlying immune suppression. Successful patient management …

Biofilm Formation by the Emerging Fungal Pathogen Trichosporon asahii: Development, Architecture, and Antifungal Resistance

G Di Bonaventura, A Pompilio, C Picciani… - Antimicrobial agents …, 2006 - Am Soc Microbiol
Trichosporon asahii is the most common cause of fatal disseminated trichosporonosis,
frequently associated with indwelling medical devices. Despite the use of antifungal drugs to …