Role of PARP in TNBC: Mechanism of inhibition, clinical applications, and resistance
Triple-negative breast cancer is a combative cancer type with a highly inflated histological
grade that leads to poor theragnostic value. Gene, protein, and receptor-specific targets …
grade that leads to poor theragnostic value. Gene, protein, and receptor-specific targets …
Molecular classification, treatment, and genetic biomarkers in triple-negative breast cancer: a review
B Lu, E Natarajan… - … in cancer research …, 2023 - journals.sagepub.com
Breast cancer is the most common malignancy and the second most common cause of
cancer-related mortality in women. Triple-negative breast cancers do not express estrogen …
cancer-related mortality in women. Triple-negative breast cancers do not express estrogen …
Ultrasound-enhanced theranostics of orthotopic breast cancer through a multifunctional core–shell tecto dendrimer-based nanomedicine platform
J Gong, C Song, G Li, Y Guo, Z Wang, H Guo… - Biomaterials …, 2023 - pubs.rsc.org
Design of multifunctional nanoplatforms combined with ultrasound-targeted microbubble
destruction (UTMD) technology for enhanced tumor accumulation is feasible to solve the …
destruction (UTMD) technology for enhanced tumor accumulation is feasible to solve the …
Chimeric oncolytic adenovirus armed chemokine rantes for treatment of breast cancer
L Ang, J Li, H Dong, C Wang, J Huang, M Li, M Zhao… - Bioengineering, 2022 - mdpi.com
The immunosuppressive state in the tumor microenvironment (TME) of breast cancer makes
it difficult to treat with immunotherapy. Oncolytic viruses not only lyse tumor cells but also …
it difficult to treat with immunotherapy. Oncolytic viruses not only lyse tumor cells but also …
Adaptation to hypoxia may promote therapeutic resistance to androgen receptor inhibition in triple-negative breast cancer
Triple-negative breast cancer (TNBC) surpasses other BC subtypes as the most challenging
to treat due to its lack of traditional BC biomarkers. Nearly 30% of TNBC patients express the …
to treat due to its lack of traditional BC biomarkers. Nearly 30% of TNBC patients express the …
Type 1 nuclear receptor activity in breast cancer: Translating preclinical insights to the clinic
S Kumar, A Freelander, E Lim - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is the most common cancer affecting women, and the
importance of NR function in breast cancer biology has been recognized since the turn of …
importance of NR function in breast cancer biology has been recognized since the turn of …
Anti-androgenic therapies targeting the luminal androgen receptor of a typical triple-negative breast cancer
Simple Summary The literature aims to explore anti-androgenic particulars against luminal
androgen receptor-specific triple-negative breast cancer, thus providing a concise report on …
androgen receptor-specific triple-negative breast cancer, thus providing a concise report on …
Long non-coding RNA HEIH: a novel tumor activator in multiple cancers
J Sun, M Ni - Cancer Cell International, 2021 - Springer
The last decade has witnessed the altered expression levels of long non-coding RNA HEIH
in different types of cancer. More than half of the HEIH studies in cancer have been …
in different types of cancer. More than half of the HEIH studies in cancer have been …
Translational implications of dysregulated pathways and microRNA regulation in quadruple-negative breast cancer
A Qattan, T Al-Tweigeri, K Suleman - Biomedicines, 2022 - mdpi.com
Triple-negative breast cancers (HER2−, ER−, PR−) continue to present a unique treatment
challenge and carry unfavorable prognoses. The elucidation of novel therapeutic targets has …
challenge and carry unfavorable prognoses. The elucidation of novel therapeutic targets has …
Molecular features of androgen-receptor low, estrogen receptor-negative breast cancers in the Carolina breast cancer study
Purpose Androgen receptor (AR) expression is absent in 40–90% of estrogen receptor (ER)-
negative breast cancers. The prognostic value of AR in ER-negative patients and …
negative breast cancers. The prognostic value of AR in ER-negative patients and …