Identification of a polycomb responsive region in human HoxA cluster and its long-range interaction with polycomb enriched genomic regions

A Verma, R Arya, V Brahmachari - Gene, 2022 - Elsevier
Polycomb and Trithorax group proteins (PcG, TrxG) epigenetically regulate developmental
genes. These proteins bind with specific DNA elements, the Polycomb Response Element …

Three classes of response elements for human PRC2 and MLL1/2–Trithorax complexes

J Du, B Kirk, J Zeng, J Ma, Q Wang - Nucleic acids research, 2018 - academic.oup.com
Abstract Polycomb group (PcG) and Trithorax group (TrxG) proteins are essential for
maintaining epigenetic memory in both embryonic stem cells and differentiated cells. To …

[PDF][PDF] Epigenetic regulation and transcriptional memory in development; selection facilitating prudence

A Verma, J Maini, S Jain, M Ghasemi, S Kohli… - International Journal of …, 2020 - ijdb.ehu.eus
PASS-like Trr MLL3/4 H3K4 methylation Lethality, rough eyes Sedkov et al., 1999; 2003 Utx
UTX H3K27 demethylation Lethality, rough eyes Denton et al., 2013; Herz et al., 2010 ASH1 …

Human PRE-PIK3C2B exhibits long-range intra- and inter-chromosomal interactions with genomic regions enriched in repressive marks

J Maini, AK Pathak, K Bhattacharyya, N Kumar… - bioRxiv, 2020 - biorxiv.org
Abstract Human PRE-PIK3C2B is a dual nature polycomb response element that interacts
with both polycomb as well as trithorax members. In the current study, using 4C-Seq (C …

Mutations in the PIK3C2B, ERBB3, KIT, and MLH1 Genes and their Relationship with Resistance to Temozolomide in Patients with High-grade Gliomas

LDO Gómez, HJC Martínez, PMA Florez, DAG Pareja… - 2023 - preprints.org
Background. The treatment for patients with high-grade gliomas includes radiation therapy
and temozolomide. However, some patients do not respond to temozolomide because they …

Genetic and physical interaction of Drosophila Ino80 with Polycomb Responsive Element

M Ghasemi, J Maini, S Jain, V Dasari, R Mishra… - bioRxiv, 2019 - biorxiv.org
The chromatin remodeling protein, dIno80 (Drosophila Ino80) regulates homeotic genes.
We show that Ino80, along with Trx and ETP (Enhancer of Trithorax and Polycomb) proteins …