Inflammation is the body's response to injury and infection, involving a complex biological
response of the somatosensory, immune, autonomic, and vascular systems. Inflammatory …

Pain is the major symptom of osteoarthritis (OA) and is an important factor in strategies to
manage this disease. However, the current standard of care does not provide satisfactory …

2. Methods This is a narrative review based on the authors' research and on that of groups
working in the same area. Given the vast amount of data in the field, it is not possible to …

Background Chronic inflammatory pain significantly reduces the quality of life and lacks
effective interventions. In recent years, human umbilical cord mesenchymal stem cells (huc …

In the central nervous system (CNS), astrocytes form networks interconnected by gap
junctions made from connexins of the subtypes Cx30 and Cx43. When unopposed by an …

Over the years, electroconductive hydrogels (ECHs) have been extensively applied for
stimulating nerve regeneration and restoring locomotor function after peripheral nerve injury …

Functional foods include enhanced, enriched, fortified, or whole foods that impart health
benefits beyond their nutritional value, particularly when consumed as part of a varied diet …

Chemotherapy-induced peripheral neuropathy (CIPN) remains a pressing clinical problem;
however, our understanding of sexual dimorphism in CIPN remains unclear. Emerging …

Many chronic pain conditions show sex differences in their epidemiology. This could be
attributed to sex-dependent differential expression of genes (DEGs) involved in nociceptive …

Background Chronic neuropathic pain is a frequent sequel to peripheral nerve injury and
maladaptive nervous system function. Divanillyl sulfone (DS), a novel structural derivative of …