Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy are caused by
mutations in the dystrophin-encoding DMD gene. Large deletions and duplications are most …

Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy in
childhood. It is caused by mutations of the DMD gene, leading to progressive muscle …

Duchenne muscular dystrophy (DMD), the most severe form of dystrophinopathy, is quite
homogeneous with regards to its causative biochemical defect, ie, complete dystrophin …

Osteopontin (OPN) is an extracellular matrix protein that is overexpressed in various cancers
and promotes oncogenic features including cell proliferation, survival, migration, and …

In 2010, Care Considerations for Duchenne Muscular Dystrophy, sponsored by the Centers
for Disease Control and Prevention, was published in Lancet Neurology, and in 2018, these …

The life-limiting complications of Duchenne muscular dystrophy (DMD) include loss of lung
function and progressive cardiomyopathy; when patients are treated with assisted …

Numerous biomarkers have been unveiled in the rapidly evolving biomarker discovery field,
with an aim to improve the clinical management of disorders. In rare diseases, such as …

Dystrophinopathies are x-linked muscular disorders which emerge from mutations in the
Dystrophin gene, including Duchenne and Becker muscular dystrophy, and dilated …

The muscular dystrophies are a heterogeneous group of disorders defined by dystrophic
pathologic features on muscle biopsy. Clinically, they are characterized by progressive …

Patients with Duchenne muscular dystrophy (DMD) show clinically relevant phenotypic
variability, despite sharing the same primary biochemical defect (dystrophin deficiency) …