Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …

Prostate cancer (PC) represents the most diagnosed and the second most lethal cancer in
men worldwide. Its development and progression occur in concert with alterations in the …

Benign prostatic hyperplasia and prostate cancer are tumoral pathologies characterized by
the overexpression of inflammatory processes. The exploration of tumor microenvironment …

Simple Summary Prostate cancer (PCa) is the second most frequent type of cancer in men
worldwide. Treatment options for early-stage PCa include external beam radiation therapy …

Dysregulation of alternative splicing in prostate cancer is linked to transcriptional programs
activated by AR, ERG, FOXA1, and MYC. Here, we show that FOXA1 functions as the …

Prostate cancer (PC) is the most prevalent male urogenital cancer worldwide. PC patients
presenting an advanced or metastatic cancer succumb to the disease, even after therapeutic …

The number of cancer cases worldwide keeps growing unstoppably, despite the undeniable
advances achieved by basic research and clinical practice. Urologic tumors, including some …

The vast majority of new prostate cancer diagnoses are low-grade tumors that are monitored
by active surveillance rather than undergoing immediate treatment. However, a subset of …

Genomic and transcriptomic data have been generated across a wide range of prostate
cancer (PCa) study cohorts. These data can be used to better characterize the molecular …

Background The SII (systemic immune-inflammation index) has been extensively reported to
have a prognostic value in prostate cancer (PCa), despite the unconformable results. The …