Impairment of the blood–brain barrier (BBB) integrity is implicated in the numerous
neurological disorders associated with neuroinflammation, neurodegeneration and aging. It …

Although fermentation probably originally developed as a means of preserving food
substrates, many fermented foods (FFs), and components therein, are thought to have a …

The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

The enteric nervous system is largely autonomous, and the central nervous system is
compartmentalized behind the blood-brain barrier. Yet the intestinal microbiota shapes gut …

The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

The advent of highthroughput 'omics' technologies has improved our knowledge of gut
microbiome in human health and disease, including Alzheimer's disease (AD), a …

Abstract Background Aberrant tryptophan (Trp)-kynurenine (Kyn) metabolism has been
implicated in the pathogenesis of human disease. In particular, populations with long-term …

Many scientific studies reveal a significant connection between human intestinal microbiota,
eating habits, and the development of chronic-degenerative diseases; therefore, alterations …

Autism Spectrum Disorder (ASD), a neurodevelopmental disorder characterized by
persistent deficits in social interaction and communication, manifests in early childhood and …

Diabetic cognitive decline has been associated with the gut microbial disorders, but its
potential gut-brain axis mechanisms remain unclear. Herein we transplanted the gut …