Statins, a class of cholesterol-lowering drugs, have consistently demonstrated pleiotropic
effects in both preclinical and clinical studies. Outside of inhibiting the production of …

Objective Preclinical data and recent epidemiological studies suggest that statins have
antiproliferative and antimetastatic effects in various cancer cells, and reduce cancer …

Biological metal-organic frameworks (BioMOFs) are hybrid compounds in which metal
nodes are linked to biocompatible organic ligands and have potential for medical …

Each year, there is a high mortality rate due to pancreatic cancer. Thus, the current study
was undertaken to evaluate the effect of diphenhydramine (DPH) against pancreatic cancer …

Resistance to induction of apoptosis is a major obstacle for bladder cancer treatment. Bcl-2
is thought to be involved in anti-apoptotic signaling. In this study, we investigated the effect …

Background: Previous studies on the association between statin use and survival outcomes
in gynecologic cancers have presented conflicting results. No independent studies to …

Simvastatin, which is widely used in the prevention and treatment of hyperlipidemia-
associated diseases, has been reported to enhance the survival of retinal ganglion cells …

Statins are drugs traditionally used to lower cholesterol levels in blood. At concentrations
100-to 500-fold higher than those needed for reaching cholesterol lowering activity, they …

The cardiovascular and mortality benefit of statins, a class of cholesterol-lowering
medications, represents one of the major medical breakthroughs of the 20th century. Further …

The aim of this study was to evaluate the effect of curcumin combined with Lactobacillus
rhamnosus GG cell-free supernatant (LGG CFS) on the proliferation and induction of …