Infections are a major threat to human reproductive health, and infections in pregnancy can
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …

Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …

The clinical outcome of Plasmodium falciparum infections ranges from asymptomatic
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …

Malaria is a major global health problem. Pregnant women are susceptible to infection
regardless of previously acquired immunity. Placental malaria is caused by parasites …

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family plays a central
role in antigenic variation and cytoadhesion of P. falciparum infected erythrocytes. PfEMP1 …

Cerebral Plasmodium falciparum malaria is characterized by adhesion of infected
erythrocytes (IEs) to the cerebral microvasculature. This has been linked to parasites …

Placental malaria is caused by Plasmodium falciparum–infected erythrocytes that bind to
placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var …

Plasmodium falciparum malaria remains one of the world's leading causes of human
suffering and poverty. Each year, the disease takes 1–3 million lives, mainly in sub-Saharan …

Sequence diversity in pathogen antigens is an obstacle to the development of interventions
against many infectious diseases. In malaria caused by Plasmodium falciparum, the PfEMP1 …

Every year, millions of people are infected with malaria, resulting in significant economic
losses to the developing and developed nations. The malaria parasite pursues a …