Since it suppresses breathing much less than most other available anesthetics,[38] ketamine
is used in medicine as an anesthetic; however, due to the hallucinations it may cause, it is …

Objective: To investigate risk factors, treatment modalities, and clinical outcomes of
metformin-associated lactic acidosis (MALA). Method: In this case-control study, type 2 …

Introduction: Metformin is the best proven first-line treatment for type 2 diabetes (T2DM),
based on both national and international guidelines. The present systematic review is aimed …

A 33-year-old woman with unspecified developmental delay is brought to the ED after her
friend called EMS for a wellness check and for poor living conditions. There is no collateral …

We read with great interest the letter by Drs. Wang and Hoffman and appreciate the
engagement with our research. Our study used a systematic review and meta-analysis …

Background: In a world where the prevalence of Diabetes is ever increasing metformin plays
an important role in the management of the disease. The most feared adverse effect of …

Acute overdose of metformin can show potentially fatal lactic acidosis. Management should
be directed towards close monitoring of renal function and hemodynamics. Patients may …

We read with interest the recent systematic review of metformin-associated lactic acidosis
(MALA)[1]. While the prognostic utility of nadir pH and peak serum lactate concentration for …

Background Surprisingly, despite the high prevalence of metformin use in type 2 diabetes
(T2D) patients with heart disease, limited safety data is available regarding metformin use in …

抄録 メトホルミン服用患者に生じる乳酸アシドーシスを総じてメトホルミン関連乳酸アシドーシス
(metforminassociated lactic acidosis, 以下 MALA) と称し, 合併時の死亡率は高い …