Abstract N-acetyl-L-cysteine (NAC) is a compound of increasing interest in the treatment of
psychiatric disorders. Primarily through its antioxidant, anti-inflammatory, and glutamate …

Obsessive-compulsive disorder (OCD) can present a significant management challenge to
the clinical psychiatrist. OCD affects approximately 1.3% of the population in any given year …

Serotonin reuptake inhibitor (SRI) medications are well established as first-line
pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However …

Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm.
Growing evidence suggests that the neurocognitive mechanisms mediating behavioral …

ABSTRACT Introduction: N-acetylcysteine (NAC) is widely known for its role as a mucolytic
and as an antidote to paracetamol overdose. There is increasing interest in the use of NAC …

What is known and objective N‐acetylcysteine (NAC) has been proposed as a potential
therapy for obsessive–compulsive disorder (OCD) as it may regulate the exchange of …

N‐acetylcysteine (NAC) is a well‐known and safe mucolytic agent, also used in patients with
paracetamol overdose. In addition to these effects, recent preclinical and clinical studies …

Background and Objectives Recent neurobiological evidences along with clinical
observations justify the use of N‐acetylcysteine (NAC) as a medication for craving. The …

Glutamate is a ubiquitous excitatory neurotransmitter, which is involved in normal
physiology, a variety of central nervous system (CNS) functions, including excitotoxicity and …

Objective: To evaluate the efficacy of serotonin reuptake inhibitor (SRI) augmentation with N-
acetylcysteine (NAC), a glutamate modulator and antioxidant medication, for treatment …