Organocatalytic Atroposelective Dynamic Kinetic Resolution Involving Ring Manipulations

Q Shi, F Fang, DJ Cheng - Advanced Synthesis & Catalysis, 2024 - Wiley Online Library
Axially chiral architectures exist widely in natural products, biologically relevant molecules,
chiral ligands and catalysts as well as functional materials. Therefore, catalytic asymmetric …

Developing biarylhemiboronic esters for biaryl atropisomer synthesis via dynamic kinetic atroposelective Suzuki–Miyaura cross-coupling

Y Yang, C Wu, J Xing, X Dou - Journal of the American Chemical …, 2024 - ACS Publications
We herein introduce biarylhemiboronic esters as a new type of bridged biaryl reagent for
asymmetric synthesis of axially chiral biaryl structures, and the palladium-catalyzed …

Development of Configurationally Labile Biaryl Reagents for Atropisomer Synthesis

C Wu, Y Jin, X Zhang, R Gao… - European Journal of …, 2024 - Wiley Online Library
Axially chiral biaryl scaffolds are important in pharmaceuticals, natural products, and
asymmetric synthesis. Atroposelective ring‐opening of configurationally labile biaryl …

Nickel‐Catalyzed Chemoselective Carbomagnesiation for Atroposelective Ring‐Opening Difunctionalization

T Sun, L Guo, Q Li, ZC Cao - … Chemie International Edition, 2024 - Wiley Online Library
There is a pressing need for methods that can connect enantioenriched organic compounds
with readily accessible building blocks via asymmetric functionalization of unreactive …

Chiral Brønsted Acid-Catalyzed Kinetic Resolution of Sulfoximines for the Synthesis of Benzothiadiazine-1-Oxides

Y Chen, S Huang, T Wang, J Li, Y Zhao… - The Journal of …, 2024 - ACS Publications
Benzothiadiazine-1-oxide scaffolds with S-stereogenic centers are prevalent in bioactive
and pharmaceutical molecules. Reported works mainly focused on the metal-catalyzed …