One of the most exciting developments in Raman spectroscopy in the last decade has been
its application to cells and tissues for diagnostic and pharmaceutical applications, and in …

Abstract Two-dimensional (2D) cell cultures, in which cells grow in flat layers on plastic
surfaces, are considered the standard model for use in drug screening and for biological …

With the ever-increasing use of 3D cell models toward studying bio-nano interactions and
offering alternatives to traditional 2D in vitro and in vivo experiments, methods to image …

Low level light therapy receives increasing interest in the fields of tissue regeneration and
wound healing. Several in vivo studies demonstrated the positive effects of LLLT on …

Vascular network engineering is essential for nutrient delivery to tissue-engineered
constructs and, consequently, their survival. In addition, the functionality of tissues also …

The current standard preclinical oncology models are not able to fully recapitulate
therapeutic targets and clinically relevant disease biology, evidenced by the 90% attrition …

Since 2011, phenotypic screening has been a trend in the pharmaceutical industry as well
as in academia. This renaissance was triggered by analyses that suggested that phenotypic …

The Raman effect was predicted by Schmekal 1 in 1923 and independently discovered in
1928 by two Indian physicists, Raman and Krishna. 2, 3 In principle, monochromatic light is …

The high population growth rate, massive animal food consumption, fast economic progress,
and limited food resources could lead to a food crisis in the future. There is a huge …

Live cell Raman micro-spectroscopy is emerging as a promising bioanalytical technique for
label-free discrimination of a range of different cell types (eg cancer cells and fibroblasts) …