Bridging the In Vitro to In Vivo gap: Using the Chick Embryo Model to Accelerate Nanoparticle Validation and Qualification for In Vivo studies
We postulate that nanoparticles (NPs) for use in therapeutic applications have largely not
realized their clinical potential due to an overall inability to use in vitro results to predict NP …
realized their clinical potential due to an overall inability to use in vitro results to predict NP …
How to xenograft cancer cells on the chorioallantoic membrane of a fertilized hen's egg and its visualization by PET/CT and MRI
J Schulze, D Librizzi, L Bender, J Jedelská… - ACS applied bio …, 2023 - ACS Publications
The chorioallantoic membrane (CAM) of fertilized hen's eggs represents a unique and
alternative model for cancer research. The CAM model provides an optimal platform for …
alternative model for cancer research. The CAM model provides an optimal platform for …
[HTML][HTML] In ovo model in cancer research and tumor immunology
L Miebach, J Berner, S Bekeschus - Frontiers in Immunology, 2022 - frontiersin.org
Considering cancer not only as malignant cells on their own but as a complex disease in
which tumor cells interact and communicate with their microenvironment has motivated the …
which tumor cells interact and communicate with their microenvironment has motivated the …
Biomarkers and 3D models predicting response to immune checkpoint blockade in head and neck cancer
A Affolter, J Kern, K Bieback… - International …, 2022 - spandidos-publications.com
Immunotherapy has evolved into a powerful tool in the fight against a number of types of
cancer, including head and neck squamous cell carcinomas (HNSCC). Although checkpoint …
cancer, including head and neck squamous cell carcinomas (HNSCC). Although checkpoint …
Chorioallantoic membrane assay at the cross-roads of adipose-tissue-derived stem cell research
D Oliinyk, A Eigenberger, O Felthaus, S Haerteis… - Cells, 2023 - mdpi.com
With a history of more than 100 years of different applications in various scientific fields, the
chicken chorioallantoic membrane (CAM) assay has proven itself to be an exceptional …
chicken chorioallantoic membrane (CAM) assay has proven itself to be an exceptional …
Exploring the predictive power of jejunal microbiome composition in clinical and subclinical necrotic enteritis caused by Clostridium perfringens: insights from a …
Background Necrotic enteritis (NE) is a severe intestinal infection that affects both humans
and poultry. It is caused by the bacterium Clostridium perfringens (CP), but the precise …
and poultry. It is caused by the bacterium Clostridium perfringens (CP), but the precise …
PD-1/PD-L1 Checkpoint Inhibitors Are Active in the Chicken Embryo Model and Show Antitumor Efficacy In Ovo
Y Wang, X Rousset, C Prunier, P Garcia, E Dosda… - Cancers, 2022 - mdpi.com
Simple Summary Cancer immunotherapy, also known as immuno-oncology (IO), has made
impressive progress in recent decades and is becoming an essential approach for cancer …
impressive progress in recent decades and is becoming an essential approach for cancer …
The chick embryo chorioallantoic membrane patient-derived xenograft (PDX) model
D Ribatti - Pathology-Research and Practice, 2023 - Elsevier
The chick embryo chorioallantoic membrane (CAM) CAM is an extraembryonic membrane
generated by the fusion of the chorion with the vascularized allantoic membrane. It performs …
generated by the fusion of the chorion with the vascularized allantoic membrane. It performs …
Human Monocytes Are Suitable Carriers for the Delivery of Oncolytic Herpes Simplex Virus Type 1 In Vitro and in a Chicken Embryo Chorioallantoic Membrane Model …
A Reale, L Krutzke, M Cadamuro, A Vitiello… - International Journal of …, 2023 - mdpi.com
Oncolytic viruses (OVs) are promising therapeutics for tumors with a poor prognosis. An OV
based on herpes simplex virus type 1 (oHSV-1), talimogene laherparepvec (T-VEC), has …
based on herpes simplex virus type 1 (oHSV-1), talimogene laherparepvec (T-VEC), has …