Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …

Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …

Primary aldosteronism (PA) is a condition that is still largely overlooked, resulting in a
considerable burden of mortality and morbidity. This is despite decades of clinical and …

Several forms of secondary hypertension carry a high risk of cardiac morbidity and mortality.
Evaluation of cardiac phenotypes in secondary hypertension provides a unique opportunity …

Context Primary aldosteronism (PA) is one of the most common causes of secondary
hypertension, but the comparative outcomes of targeted treatment remain unclear …

Aldosterone and cortisol serve important roles in the pathogenesis of cardiovascular
diseases and metabolic disorders. Epigenetics is a mechanism to control enzyme …

Angiotensin II, a major culprit in cardiovascular disease, activates mediators that are also
involved in pathological cardiac remodeling. In this context, we aimed at investigating the …

BACKGROUND: About 10% of patients with arterial hypertension have a positive screening
test for primary aldosteronism (PA) and 50% to 70% of them have a negative confirmatory …

Abnormalities in G-protein-gated inwardly rectifying potassium (GIRK) channels have been
implicated in diseased states of the cardiovascular system; however, the role of GIRK4 (Kir3 …

Our prior study has suggested that percutaneous superselective adrenal arterial
embolization (SAAE) with ethanol reduces blood pressure in patients with primary …