Novel CRISPR–Cas systems: an updated review of the current achievements, applications, and future research perspectives

S Nidhi, U Anand, P Oleksak, P Tripathi, JA Lal… - International journal of …, 2021 - mdpi.com
According to Darwin's theory, endless evolution leads to a revolution. One such example is
the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an …

[HTML][HTML] The genome editing revolution

J Van der Oost, C Patinios - Trends in Biotechnology, 2023 - cell.com
A series of spectacular scientific discoveries and technological advances in the second half
of the 20th century have provided the basis for the ongoing genome editing revolution. The …

Current state and future prospects of pure mycelium materials

S Vandelook, E Elsacker, A Van Wylick… - Fungal biology and …, 2021 - Springer
In the context of the ongoing transition from a linear to a circular economy, ecologically
friendly renewable solutions are put in place. Filamentous fungi can be grown on various …

Microbial pigments in the food industry—challenges and the way forward

T Sen, CJ Barrow, SK Deshmukh - Frontiers in nutrition, 2019 - frontiersin.org
Developing new colors for the food industry is challenging, as colorants need to be
compatible with a food flavors, safety, and nutritional value, and which ultimately have a …

Escherichia coli as a host for metabolic engineering

S Pontrelli, TY Chiu, EI Lan, FYH Chen, P Chang… - Metabolic …, 2018 - Elsevier
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

[HTML][HTML] Bioremediation of lignin derivatives and phenolics in wastewater with lignin modifying enzymes: Status, opportunities and challenges

AK Singh, M Bilal, HMN Iqbal, AS Meyer… - Science of the Total …, 2021 - Elsevier
Lignin modifying enzymes from fungi and bacteria are potential biocatalysts for sustainable
mitigation of different potentially toxic pollutants in wastewater. Notably, the paper and pulp …

Modular (de) construction of complex bacterial phenotypes by CRISPR/nCas9-assisted, multiplex cytidine base-editing

DC Volke, RA Martino, E Kozaeva, AM Smania… - Nature …, 2022 - nature.com
CRISPR/Cas technologies constitute a powerful tool for genome engineering, yet their use
in non-traditional bacteria depends on host factors or exogenous recombinases, which limits …

CRISPR technology is revolutionizing the improvement of tomato and other fruit crops

T Wang, H Zhang, H Zhu - Horticulture research, 2019 - academic.oup.com
Fruits are major sources of essential nutrients and serve as staple foods in some areas of
the world. The increasing human population and changes in climate experienced worldwide …

Large-scale production of enzymes for biotechnology uses

A Fasim, VS More, SS More - Current opinion in biotechnology, 2021 - Elsevier
Enzymes are biocatalysts that speed up the chemical reaction to obtain the final valuable
product/s. Biotechnology has revolutionized the use of traditional enzymes to be applicable …

Grand research challenges for sustainable industrial biotechnology

AJJ Straathof, SA Wahl, KR Benjamin, R Takors… - Trends in …, 2019 - cell.com
Future manufacturing will focus on new, improved products as well as on new and
enhanced production methods. Recent biotechnological and scientific advances, such as …