The metabolite profile of fresh Goji berries from two cultivars, namely Big Lifeberry (BL) and
Sweet Lifeberry (SL), grown in the Lazio region (Central Italy) and harvested at two different …

Previous studies have indicated a complex interplay between the nitric oxide (NO) pain
signaling pathways and hormonal signaling pathways in the body. This article delineates the …

Infants admitted to neonatal intensive care units are repeatedly stimulated by painful events,
especially if intubated. Preterm infants are known to have greater pain perception than full …

Inflammatory mechanisms are proposed to play a role in l-DOPA-induced dyskinesia.
Cyclooxygenase-2 (COX2) contributes to inflammation pathways in the periphery and is …

A novel series of 12 antipyrine derivatives containing 1, 3, 4-oxadiazoles (4a-d), 1, 3, 4-
thiadiazoles (6a-d), and pyrimidines (8a-d), was preparedand assessed for its potential in …

Background/Aim: Periodontitis is a chronic inflammatory disease linked to various systemic
age-related conditions. It is known that α, β-unsaturated carbonyl compounds such as …

Introduction: D-pinitol, a naturally occurring inositol, has diverse biological activities like
antioxidant, antimicrobial and anticancer activities. This study aimed to evaluate anti …

Sesamin, one of the most abundant lignans in sesame seeds and oils, is well known for
neuroprotective activity. However, its effects on toll-like-receptor 4 (TLR4), the key innate …

Myracrodruon urundeuva Fr. Allem.(Anacardiaceae) is a tree popularly known as the
“aroeira-do-sertão”, native to the caatinga and cerrado biomes, with a natural dispersion …

In clinical practice, inflammatory pain is an important, unresolved health problem, despite
the utilization of non-steroidal anti-inflammatory drugs (NSAIDs). In the last decade, different …