Inhaled corticosteroids in COPD: friend or foe?
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …
Prevention of acute exacerbations of COPD: American college of chest physicians and Canadian thoracic society guideline
GJ Criner, J Bourbeau, RL Diekemper, DR Ouellette… - Chest, 2015 - Elsevier
BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …
[HTML][HTML] Indacaterol–glycopyrronium versus salmeterol–fluticasone for COPD
JA Wedzicha, D Banerji, KR Chapman… - … England Journal of …, 2016 - Mass Medical Soc
Background Most guidelines recommend either a long-acting beta-agonist (LABA) plus an
inhaled glucocorticoid or a long-acting muscarinic antagonist (LAMA) as the first-choice …
inhaled glucocorticoid or a long-acting muscarinic antagonist (LAMA) as the first-choice …
Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the …
H Watz, K Tetzlaff, EFM Wouters, A Kirsten… - The lancet Respiratory …, 2016 - thelancet.com
Background Blood eosinophil counts might predict response to inhaled corticosteroids (ICS)
in patients with chronic obstructive pulmonary disease (COPD) and a history of …
in patients with chronic obstructive pulmonary disease (COPD) and a history of …
Long-term triple therapy de-escalation to indacaterol/glycopyrronium in patients with chronic obstructive pulmonary disease (SUNSET): a randomized, double-blind …
KR Chapman, JR Hurst, SM Frent, M Larbig… - American journal of …, 2018 - atsjournals.org
Rationale: There are no studies on withdrawal of inhaled corticosteroids in patients on long-
term triple therapy in the absence of frequent exacerbations. Objectives: To evaluate the …
term triple therapy in the absence of frequent exacerbations. Objectives: To evaluate the …
Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns
D Price, D West, G Brusselle… - … journal of chronic …, 2014 - Taylor & Francis
Background Despite the availability of national and international guidelines, evidence
suggests that chronic obstructive pulmonary disease (COPD) treatment is not always …
suggests that chronic obstructive pulmonary disease (COPD) treatment is not always …
Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management
Chronic obstructive pulmonary disease (COPD) is a common, complex, and heterogeneous
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …
Blood eosinophils and response to maintenance chronic obstructive pulmonary disease treatment. Data from the FLAME trial
N Roche, KR Chapman, CF Vogelmeier… - American journal of …, 2017 - atsjournals.org
Rationale: Post hoc analyses suggest that blood eosinophils have potential as a predictive
biomarker of inhaled corticosteroid efficacy in the management of chronic obstructive …
biomarker of inhaled corticosteroid efficacy in the management of chronic obstructive …
Intrinsically stretchable conductive self-healable organogels for strain, pressure, temperature, and humidity sensing
Intrinsically stretchable conductive self-healable organogels containing poly (lipoic acid),
Al3+ ion, tannic acid, and reduced graphene oxide are produced in this report. These …
Al3+ ion, tannic acid, and reduced graphene oxide are produced in this report. These …
The inevitable drift to triple therapy in COPD: an analysis of prescribing pathways in the UK
G Brusselle, D Price, K Gruffydd-Jones… - … journal of chronic …, 2015 - Taylor & Francis
Background Real-world prescription pathways leading to triple therapy (TT)(inhaled
corticosteroid [ICS] plus long-acting β2-agonist bronchodilator [LABA] plus long-acting …
corticosteroid [ICS] plus long-acting β2-agonist bronchodilator [LABA] plus long-acting …