Recent updates on 1, 2, 3-triazole-containing hybrids with in vivo therapeutic potential against cancers: A mini-review
S Zhao, J Liu, Z Lv, G Zhang, Z Xu - European Journal of Medicinal …, 2023 - Elsevier
Triazole moiety which is usually constructed by highly versatile, efficacious and selective
copper-catalyzed azide-alkyne cycloaddition not only can act as a linker to connect different …
copper-catalyzed azide-alkyne cycloaddition not only can act as a linker to connect different …
The 1, 2, 3-triazole 'all-in-one'ring system in drug discovery: A good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool
ABSTRACT Introduction The 1, 2, 3-triazole ring occupies an important space in medicinal
chemistry due to its unique structural properties, synthetic versatility and pharmacological …
chemistry due to its unique structural properties, synthetic versatility and pharmacological …
Synthesis of novel pyrido [2, 3-d] pyrimidine-thiazolidine-1, 2, 3-triazoles: Potent EGFR targeting anticancer agents
SR Bandi, R Kapavarapu, R Palabindela… - Journal of Molecular …, 2023 - Elsevier
In this study, we designed and synthesized a number of novel pyrido [2, 3-d] pyrimidine-
thiazolidine-1, 2, 3-triazole derivatives and investigated them in vitro for their inhibitory …
thiazolidine-1, 2, 3-triazole derivatives and investigated them in vitro for their inhibitory …
Erlotinib-Containing Benzenesulfonamides As Anti-Helicobacter Pylori Agents Through Carbonic Anhydrase Inhibition
G Benito, I D'Agostino, S Carradori… - Future Medicinal …, 2023 - Taylor & Francis
Aim: Development of dual-acting antibacterial agents containing Erlotinib, a recognized
EGFR inhibitor used as an anticancer agent, with differently spaced benzenesulfonamide …
EGFR inhibitor used as an anticancer agent, with differently spaced benzenesulfonamide …
Design, synthesis and biological evaluation of erlotinib-based IDO1 inhibitors
X Hou, X Gong, L Mao, G Sun, J Yang - Frontiers in Pharmacology, 2022 - frontiersin.org
Erlotinib is a highly specific and reversible epidermal growth factor receptor tyrosine kinase
inhibitor for the targeted therapy of non-small-cell lung cancer (NSCLC) However, the …
inhibitor for the targeted therapy of non-small-cell lung cancer (NSCLC) However, the …
Synthesis and biological evaluation of novel demethylzeylasteral derivatives as potential anticancer agents
X Sun, L Xing, J Yuan, E Wang, Y Ding, R Sheng… - Fitoterapia, 2023 - Elsevier
Demethylzeylasteral (DEM), a class of terpenoids isolated from natural plants, frequently
exhibits moderate or limited inhibitory effect on tumor growth across multiple cancer types …
exhibits moderate or limited inhibitory effect on tumor growth across multiple cancer types …
Synthesis and activity study of novel N, N-diphenylurea derivatives as IDO1 inhibitors
XX Hou, ZY Wu, A Zhan, E Gao, LF Mao… - Frontiers in …, 2023 - frontiersin.org
Indoleamine 2, 3-dioxygenase 1 (IDO1) has attracted much attention in the field of cancer
immunotherapy as an immunomodulatory enzyme. To identify potential IDO1 inhibitors, a …
immunotherapy as an immunomodulatory enzyme. To identify potential IDO1 inhibitors, a …