Next-generation CRISPR-based diagnostic tools for human diseases

T Wang, Z Wang, L Bai, X Zhang, H Zhang… - TrAC Trends in …, 2023 - Elsevier
Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …

Emerging strategies and therapeutic innovations for combating drug resistance in Staphylococcus aureus strains: A comprehensive review

M Gopikrishnan, S Haryini - Journal of Basic Microbiology, 2024 - Wiley Online Library
In recent years, antibiotic therapy has encountered significant challenges due to the rapid
emergence of multidrug resistance among bacteria responsible for life‐threatening …

Role of nuc gene in Staphylococcus aureus to phagocytic activity in different cattle infections

HK Ibraheim, RA Fayez, AS Jasim, HAJ Gharban - Open Veterinary Journal, 2023 - ajol.info
Background: Staphylococcus aureus is a typical pathogenic agent that causes several
morbidities and mortalities which variable largely following the severity of bacteria and …

Application of CRISPR/Cas12a in the rapid detection of pathogens

Y Wang, T Yang, G Liu, L Xie, J Guo, W Xiong - Clinica Chimica Acta, 2023 - Elsevier
The combination of clustered regularly interspaced short palindromic repeats (CRISPR) and
its associated Cas protein is an effective gene-editing instrument. Among them, the CRISPR …

Cas-based bacterial detection: recent advances and perspectives

H Lan, W Shu, D Jiang, L Yu, G Xu - Analyst, 2024 - pubs.rsc.org
Persistent bacterial infections pose a formidable threat to global health, contributing to
widespread challenges in areas such as food safety, medical hygiene, and animal …

[HTML][HTML] Isothermal Amplification and CRISPR/Cas12a-System-Based Assay for Rapid, Sensitive and Visual Detection of Staphylococcus aureus

D Xu, H Zeng, W Wu, H Liu, J Wang - Foods, 2023 - mdpi.com
Staphylococcus aureus exists widely in the natural environment and is one of the main food-
borne pathogenic microorganisms causing human bacteremia. For safe food management …

Recent progress on the CRISPR/Cas system in optical biosensors

B Li, G Zhai, Y Dong, L Wang, P Ma - Analytical Methods, 2024 - pubs.rsc.org
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
associated (Cas) protein systems are adaptive immune systems unique to archaea and …