[HTML][HTML] Role of EGFR in the Nervous System

R Romano, C Bucci - Cells, 2020 - mdpi.com
Epidermal growth factor receptor (EGFR) is the first discovered member of the receptor
tyrosine kinase superfamily and plays a fundamental role during embryogenesis and in …

The development of neural stem cells

S Temple - Nature, 2001 - nature.com
The discovery of stem cells that can generate neural tissue has raised new possibilities for
repairing the nervous system. A rush of papers proclaiming adult stem cell plasticity has …

Extracellular matrix: functions in the nervous system

CS Barros, SJ Franco, U Müller - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
An astonishing number of extracellular matrix glycoproteins are expressed in dynamic
patterns in the developing and adult nervous system. Neural stem cells, neurons, and glia …

[HTML][HTML] The evolving concept of a stem cell: entity or function?

HM Blau, TR Brazelton, JM Weimann - Cell, 2001 - cell.com
Entity or Function? specific adult stem cell may need to be expanded. Accordingly, adult
stem cells may not only act locally in the tissues in which they reside, but may also be …

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

A Aguirre, ME Rubio, V Gallo - Nature, 2010 - nature.com
Specialized cellular microenvironments, or 'niches', modulate stem cell properties, including
cell number, self-renewal and fate decisions,. In the adult brain, niches that maintain a …

Cell-cycle control and cortical development

C Dehay, H Kennedy - Nature Reviews Neuroscience, 2007 - nature.com
The spatio-temporal timing of the last round of mitosis, followed by the migration of
neuroblasts to the cortical plate leads to the formation of the six-layered cortex that is …

The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation

AM Bond, OG Bhalala… - Developmental …, 2012 - Wiley Online Library
The bone morphogenetic proteins (BMPs) are a group of powerful morphogens that are
critical for development of the nervous system. The effects of BMP signaling on neural stem …

Glioma stem cells: signaling, microenvironment, and therapy

BD Liebelt, T Shingu, X Zhou, J Ren… - Stem cells …, 2016 - Wiley Online Library
Glioblastoma remains the most common and devastating primary brain tumor despite
maximal therapy with surgery, chemotherapy, and radiation. The glioma stem cell (GSC) …

DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling

G Fan, K Martinowich, MH Chin, F He, SD Fouse… - 2005 - journals.biologists.com
DNA methylation is a major epigenetic factor that has been postulated to regulate cell
lineage differentiation. We report here that conditional gene deletion of the maintenance …

[HTML][HTML] From cradle to grave: the multiple roles of fibroblast growth factors in neural development

F Guillemot, C Zimmer - Neuron, 2011 - cell.com
The generation of a functional nervous system involves a multitude of steps that are
controlled by just a few families of extracellular signaling molecules. Among these, the …