Activation of the Nrf2/HO-1 signaling pathway by dimethyl fumarate ameliorates complete Freund's adjuvant-induced arthritis in rats

R Lal, J Dhaliwal, N Dhaliwal, RN Dharavath… - European Journal of …, 2021 - Elsevier
The nuclear factor erythroid 2-related factor (Nrf2) signaling pathway has recently emerged
as a novel therapeutic target in treating various diseases. Therefore, the present study …

[HTML][HTML] Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins

M Daurat, C Gauthier, K El Cheikh, LMA Ali… - Frontiers in …, 2024 - frontiersin.org
Inducing the degradation of pathological soluble antigens could be the key to greatly
enhancing the efficacy of therapeutic monoclonal antibodies (mAbs), extensively used in the …

[HTML][HTML] Presence of tumor necrosis factor-alpha in urine samples of patients with chronic low back pain undergoing chiropractic care: preliminary findings from a …

C Gevers-Montoro, M Romero-Santiago… - Frontiers in Integrative …, 2022 - frontiersin.org
Background and aims Low back pain is the leading cause of years lived with disability
worldwide. Chiropractors employ different interventions to treat low back pain, including …

Sex differences in remission rates over 24 weeks among three different biological treatments compared to conventional therapy in patients with early rheumatoid …

K Lend, RF van Vollenhoven, J Lampa… - The Lancet …, 2022 - thelancet.com
Background Rheumatoid arthritis is a chronic inflammatory disease with a well-recognised
female preponderance. In this post-hoc analysis of the NORD-STAR trial, we aimed to …

[PDF][PDF] Serum tumor necrosis factor-alpha as a competent biomarker for evaluation of disease activity in early rheumatoid arthritis

MI Illahi, S Amjad, SM Alam, ST Ahmed, M Fatima… - Cureus, 2021 - cureus.com
Aim The cytokines particularly tumor necrosis factor-alpha (TNF-α) have a substantial role in
the pathophysiology of rheumatoid arthritis (RA). The goal of this study was to evaluate the …

[HTML][HTML] In silico prediction of phytoconstituents from Ehretia laevis targeting TNF-α in arthritis

SR Yende, SK Shah, SK Arora, KS Moharir… - Digital Chinese …, 2021 - Elsevier
Objective Rheumatoid arthritis (RA) is an autoimmune disease involving the synovial lining
of the major joints. Current therapies have noteworthy side effects. Our study involved in …

Rapamycin regulates osteogenic differentiation through Parkin-mediated mitophagy in rheumatoid arthritis

Q Chen, K Fan, G Song, X Wang, J Zhang… - International …, 2022 - Elsevier
Varying degrees of bone destruction and bone loss occur in the development of rheumatoid
arthritis (RA). Nevertheless, the mechanism underlying osteoporosis in the development of …

Casein and its pepsin and trypsin hydrolysates of goat milk reduces temporomandibular joint inflammatory hypernociception in rats: Putative role for TNF-α, IL-1β, and …

SP Braga, MEF Fernandes, MM Bezerra, SR Basílio… - 2022 - researchsquare.com
Abstract Temporomandibular Disorders (TMDs) is a group of musculoskeletal and
neuromuscular conditions involving the temporomandibular joints (TMJs), the masticatory …

Functional mass cytometry for reclassification and precise diagnosis of systemic autoimmune diseases

P Rybakowska - 2021 - digibug.ugr.es
Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSC),
Sjögren's syndrome (SJS), mixed connective tissue disease (MCTD) and primary …

[PDF][PDF] ASSOCIATION OF SOME IMMUNOLOGICAL BIOMARKERS WITH RHEUMATOID ARTHRITIS PATIENTS IN THI-QAR PROVINCE

GM Hamadi - … IN PUBMED/MEDLINE, SCOPUS, EMBASE, EBSCO …, 2023 - researchgate.net
The aim: The aim of this research is to evaluate some immunological biomarkers in cases of
Rheumatoid arthritis and to verify their correlation with activity of disease among the …