Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Method to diversify cyanine chromophore functionality enables improved biomolecule tracking and intracellular imaging

SM Usama, SC Marker, DH Li… - Journal of the …, 2023 - ACS Publications
Heptamethine indocyanines are invaluable probes for near-infrared (NIR) imaging. Despite
broad use, there are only a few synthetic methods to assemble these molecules, and each …

Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma

H Luo, H Zhang, J Mao, H Cao, Y Tao, G Zhao… - Cell Death & …, 2023 - nature.com
Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …

A nanodrug combining CD47 and sonodynamic therapy efficiently inhibits osteosarcoma deterioration

M Gong, Y Huang, H Feng, J Lin, A Huang, J Hu… - Journal of Controlled …, 2023 - Elsevier
Treatments for osteosarcoma (OS) with pulmonary metastases reach a bottleneck with a
survival rate of 10–20%. The suppressive tumor associated macrophages (TAMs) and CD47 …

Radiation-induced tumor immune microenvironments and potential targets for combination therapy

S Guo, Y Yao, Y Tang, Z Xin, D Wu, C Ni… - … and Targeted Therapy, 2023 - nature.com
As one of the four major means of cancer treatment including surgery, radiotherapy (RT),
chemotherapy, immunotherapy, RT can be applied to various cancers as both a radical …

Immunomodulatory roles of selenium nanoparticles: Novel arts for potential immunotherapy strategy development

G Chen, F Yang, S Fan, H Jin, K Liao, X Li… - Frontiers in …, 2022 - frontiersin.org
Current chemotherapy strategies used in clinic appear with lots of disadvantages due to the
low targeting effects of drugs and strong side effects, which significantly restricts the drug …

Anti-tumor immune potentiation targets-engineered nanobiotechnologies: design principles and applications

R Jiao, X Lin, Q Zhang, Y Zhang, W Qin, Q Yang… - Progress in Materials …, 2023 - Elsevier
Combined therapeutic strategies hold promises in augmenting antigen release to enhance
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …

YKL-40 derived from infiltrating macrophages cooperates with GDF15 to establish an immune suppressive microenvironment in gallbladder cancer

Z Wang, S Wang, Z Jia, Y Hu, D Cao, M Yang, L Liu… - Cancer Letters, 2023 - Elsevier
Despite of the high lethality of gallbladder cancer (GBC), little is known regarding molecular
regulation of the tumor immunosuppressive microenvironment. Here, we determined tumor …

Emerging nanomedicines strategies focused on tumor microenvironment against cancer recurrence and metastasis

Y Feng, Z Liao, H Zhang, X Xie, F You, X Liao… - Chemical Engineering …, 2023 - Elsevier
Every stage of cancer metastasis, immune surveillance evasion, and therapeutic resistance
is influenced by tumor microenvironment (TME). In light of this, nanomedicines design based …