Role of pseudogenes in tumorigenesis

X Hu, L Yang, YY Mo - Cancers, 2018 - mdpi.com
Functional genomics has provided evidence that the human genome transcribes a large
number of non-coding genes in addition to protein-coding genes, including microRNAs and …

Epigenetic modification and BRAF gene mutation in thyroid carcinoma

G Huang, J Chen, J Zhou, S Xiao, W Zeng, J Xia… - Cancer cell …, 2021 - Springer
Thyroid cancer remains the most prevailing endocrine malignancy, and a progressively
increasing incidence rate has been observed in recent years, with 95% of thyroid cancer …

Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

CM Beltrami, MB Dos Reis, MC Barros-Filho… - Clinical …, 2017 - Springer
Background Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a
recent increase in incidence in many countries. Although PTC has been explored by gene …

Targeting the TSH receptor in thyroid cancer

CW Rowe, JW Paul, C Gedye… - Endocrine-Related …, 2017 - erc.bioscientifica.com
Recent advances in the arena of theranostics have necessitated a re-examining of
previously established fields. The existing paradigm of therapeutic thyroid-stimulating …

BRAF V600E Mutation Lacks Association with Poorer Clinical Prognosis in Papillary Thyroid Carcinoma

HF Lai, JF Hang, PC Kuo, CS Kuo, SF Yao… - Annals of Surgical …, 2024 - Springer
Background Previous literatures showed wide range of prevalence of BRAF V600E in
papillary thyroid carcinoma (PTC). The correlation of BRAF V600E mutation with aggressive …

Proteomics study of serum exosomes from papillary thyroid cancer patients

D Luo, S Zhan, W Xia, L Huang… - Endocrine-Related …, 2018 - erc.bioscientifica.com
Lymph node metastasis (LNM) in papillary thyroid cancer (PTC) is related to increased risk
of recurrence and poor prognosis. Tumour exosomes have been shown to be associated …

[HTML][HTML] The role of MAPK, notch and Wnt signaling pathways in papillary thyroid cancer: Evidence from a systematic review and meta-analyzing microarray datasets …

E Amjad, S Asnaashari, A Jahanban-Esfahlan… - … and Biophysics Reports, 2024 - Elsevier
Papillary thyroid cancer (PTC) is a prevalent kind of thyroid cancer (TC), with the risk of
metastasis increasing faster than any other malignancy. So, understanding the role of PTC …

Noncoding RNAs in thyroid-follicular-cell-derived carcinomas

M De Martino, F Esposito, M Capone, P Pallante… - Cancers, 2022 - mdpi.com
Simple Summary Thyroid tumors represent the most common neoplastic pathology of the
endocrine system. Mutations occurring in oncogenes and tumor suppressor genes are …

A systematic review and meta-analysis of the diagnostic performance of BRAF V600E immunohistochemistry in thyroid histopathology

R Singarayer, O Mete, L Perrier, L Thabane, SL Asa… - Endocrine …, 2019 - Springer
Immunohistochemistry (IHC) in evaluating thyroid surgical specimens may facilitate
diagnostic and prognostic evaluation, with potential therapeutic implications. We performed …

Predictive Value of BRAFV600E Mutation for Lymph Node Metastasis in Papillary Thyroid Cancer: A Meta-analysis

J Song, S Sun, F Dong, T Huang, B Wu, J Zhou - Current Medical Science, 2018 - Springer
Abstract BRAF V600E mutation has been thought to be a valuable molecular marker that
may predict a worse prognosis for papillary thyroid cancer (PTC). But whether BRAF V600E …