The conventional paradigm of nonalcoholic fatty liver disease representing the “hepatic
manifestation of the metabolic syndrome” is outdated. We identified and summarized …

Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …

So far, the connections between obesity and skeleton have been extensively explored, but
the results are inconsistent. Obesity is thought to affect bone health through a variety of …

The American Diabetes Association convened a research symposium,“Epigenetics and
Epigenomics: Implications for Diabetes and Obesity” on 17–19 November 2017 …

Appetite and body weight regulation are controlled by the central nervous system (CNS) in a
rather complicated manner. The human brain plays a central role in integrating internal and …

Introduction Insulin resistance assessment requires sophisticated methodology of difficult
application. Therefore, different estimators for this condition have been suggested. The aim …

Poor postnatal growth after preterm birth does not match the normal rapid growth in utero
and is associated with preterm morbidities. Insulin‐like growth factor 1 (IGF‐1) axis is the …

Insulin resistance and hypertension are considered as prototypical “diseases of civilization”
that are manifested in the modern environment as plentiful food and sedentary life. The …

Abstract Aims/Hypothesis Irisin is a novel, myocyte secreted, hormone that has been
proposed to mediate the beneficial effects of exercise on metabolism. Irisin is expressed, at …

Type 2 diabetes is a risk factor for developing Alzheimer's disease (AD). The underlying
mechanism that links up the two conditions seems to be the de-sensitization of insulin …