[HTML][HTML] Chlamydia trachomatis genital infections

CM O'Connell, ME Ferone - Microbial cell, 2016 - ncbi.nlm.nih.gov
Etiology, transmission and protection: Chlamydia trachomatis is the leading cause of
bacterial sexually transmitted infection (STI) globally. However, C. trachomatis also causes …

Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny

LDW Luu, V Kasimov, S Phillips, GSA Myers… - Frontiers in cellular …, 2023 - frontiersin.org
The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals, including C. trachomatis and C. pneumoniae. Since 1998, when the …

Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion

J Hadfield, SR Harris, HMB Seth-Smith… - Genome …, 2017 - genome.cshlp.org
Chlamydia trachomatis is the world's most prevalent bacterial sexually transmitted infection
and leading infectious cause of blindness, yet it is one of the least understood human …

Chlamydia trachomatis: when the virulence-associated genome backbone imports a prevalence-associated major antigen signature

V Borges, D Cordeiro, AI Salas, Z Lodhia… - Microbial …, 2019 - microbiologyresearch.org
Chlamydia trachomatis is the most prevalent sexually transmitted bacterium worldwide and
the causative agent of trachoma. Its strains are classified according to their ompA genotypes …

Genomic insights into local-scale evolution of ocular Chlamydia trachomatis strains within and between individuals in Gambian trachoma-endemic villages

E Ghasemian, N Faal, H Pickering… - Microbial …, 2024 - microbiologyresearch.org
Trachoma, a neglected tropical disease caused by Chlamydia trachomatis (Ct) serovars A–
C, is the leading infectious cause of blindness worldwide. Africa bears the highest burden …

The Impact of Lateral Gene Transfer in Chlamydia

H Marti, RJ Suchland, DD Rockey - Frontiers in cellular and infection …, 2022 - frontiersin.org
Lateral gene transfer (LGT) facilitates many processes in bacterial ecology and
pathogenesis, especially regarding pathogen evolution and the spread of antibiotic …

Chlamydiae from Down Under: The Curious Cases of Chlamydial Infections in Australia

M Jelocnik - Microorganisms, 2019 - mdpi.com
In Australia, the most researched and perhaps the most successful chlamydial species are
the human pathogen Chlamydia trachomatis, animal pathogens Chlamydia pecorum and …

Genomic analysis of MSM rectal Chlamydia trachomatis isolates identifies predicted tissue-tropic lineages generated by intraspecies lateral gene transfer-mediated …

RJ Suchland, SJ Carrell, SA Ramsey… - Infection and …, 2022 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular bacterium that causes serious diseases in
humans. Rectal infection and disease caused by this pathogen are important yet …

Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease

B Versteeg, SM Bruisten, Y Pannekoek, KA Jolley… - BMC genomics, 2018 - Springer
Abstract Background Chlamydia trachomatis (Ct) plasmid has been shown to encode genes
essential for infection. We evaluated the population structure of Ct using whole-genome …

Ammonia generation by tryptophan synthase drives a key genetic difference between genital and ocular Chlamydia trachomatis isolates

SP Sherchand, A Aiyar - Proceedings of the National …, 2019 - National Acad Sciences
A striking difference between genital and ocular clinical isolates of Chlamydia trachomatis is
that only the former express a functional tryptophan synthase and therefore can synthesize …