Antimicrobial drugs bearing guanidine moieties: A review
SH Kim, D Semenya, D Castagnolo - European Journal of Medicinal …, 2021 - Elsevier
Compounds incorporating guanidine moieties constitute a versatile class of biologically
interesting molecules with a wide array of applications. As such, guanidines have been …
interesting molecules with a wide array of applications. As such, guanidines have been …
Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
[HTML][HTML] Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review
AR Gomes, CL Varela, AS Pires… - Bioorganic …, 2023 - Elsevier
Guanidines are fascinating small nitrogen-rich organic compounds, which have been
frequently associated with a wide range of biological activities. This is mainly due to their …
frequently associated with a wide range of biological activities. This is mainly due to their …
The chemistry and biology of guanidine natural products
RGS Berlinck, S Romminger - Natural Product Reports, 2016 - pubs.rsc.org
Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382 The present
review discusses the isolation, structure determination, synthesis, biosynthesis and …
review discusses the isolation, structure determination, synthesis, biosynthesis and …
The structure, function, and mechanisms of action of enterovirus non-structural protein 2C
SH Wang, K Wang, K Zhao, SC Hua, J Du - Frontiers in microbiology, 2020 - frontiersin.org
Enteroviruses are a group of RNA viruses belonging to the family Picornaviridae. They
include human enterovirus groups A, B, C, and D as well as non-human enteroviruses …
include human enterovirus groups A, B, C, and D as well as non-human enteroviruses …
Human norovirus NS3 has RNA helicase and chaperoning activities
TF Li, M Hosmillo, H Schwanke, T Shu, Z Wang… - Journal of …, 2018 - Am Soc Microbiol
ABSTRACT RNA-remodeling proteins, including RNA helicases and chaperones, act to
remodel RNA structures and/or protein-RNA interactions and are required for all processes …
remodel RNA structures and/or protein-RNA interactions and are required for all processes …
Ebola virus VP35 has novel NTPase and helicase-like activities
T Shu, T Gan, P Bai, X Wang, Q Qian… - Nucleic Acids …, 2019 - academic.oup.com
Ebola virus (EBOV) is a non-segmented, negative-sense RNA virus (NNSV) in the family
Filoviridae, and is recognized as one of the most lethal pathogens in the planet. For RNA …
Filoviridae, and is recognized as one of the most lethal pathogens in the planet. For RNA …
Controlled Modification of Triaminoguanidine-Based μ3 Ligands in Multinuclear [VIVO]/[VVO2] Complexes and Their Catalytic Potential in the Synthesis of 2-Amino-3-cyano-4H …
Reaction of tris (2-hydroxybenzylidene)-triaminoguanidinium chloride (I· HCl) and tris (5-
bromo-2-hydroxybenzylidene)-triaminoguanidinium chloride (II· HCl) with [VIVO (acac) 2](1 …
bromo-2-hydroxybenzylidene)-triaminoguanidinium chloride (II· HCl) with [VIVO (acac) 2](1 …
Discovery and pharmacokinetics of sulfamides and guanidines as potent human arginase 1 inhibitors
R Blaszczyk, J Brzezinska, B Dymek… - ACS Medicinal …, 2020 - ACS Publications
We designed and synthesized a series of arginase inhibitors as derivatives of the well-
known 2-(S)-amino-6-boronohexanoic acid (ABH) with basic and neutral side chains in the α …
known 2-(S)-amino-6-boronohexanoic acid (ABH) with basic and neutral side chains in the α …
Novel guanidine compound against multidrug-resistant cystic fibrosis-associated bacterial species
Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections
dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and …
dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and …