Compounds incorporating guanidine moieties constitute a versatile class of biologically
interesting molecules with a wide array of applications. As such, guanidines have been …

The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

Guanidines are fascinating small nitrogen-rich organic compounds, which have been
frequently associated with a wide range of biological activities. This is mainly due to their …

Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382 The present
review discusses the isolation, structure determination, synthesis, biosynthesis and …

Enteroviruses are a group of RNA viruses belonging to the family Picornaviridae. They
include human enterovirus groups A, B, C, and D as well as non-human enteroviruses …

ABSTRACT RNA-remodeling proteins, including RNA helicases and chaperones, act to
remodel RNA structures and/or protein-RNA interactions and are required for all processes …

Ebola virus (EBOV) is a non-segmented, negative-sense RNA virus (NNSV) in the family
Filoviridae, and is recognized as one of the most lethal pathogens in the planet. For RNA …

Reaction of tris (2-hydroxybenzylidene)-triaminoguanidinium chloride (I· HCl) and tris (5-
bromo-2-hydroxybenzylidene)-triaminoguanidinium chloride (II· HCl) with [VIVO (acac) 2](1 …

We designed and synthesized a series of arginase inhibitors as derivatives of the well-
known 2-(S)-amino-6-boronohexanoic acid (ABH) with basic and neutral side chains in the α …

Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections
dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and …