[HTML][HTML] Parabrachial Calca neurons drive nociplasticity
Pain that persists beyond the time required for tissue healing and pain that arises in the
absence of tissue injury, collectively referred to as nociplastic pain, are poorly understood …
absence of tissue injury, collectively referred to as nociplastic pain, are poorly understood …
Burning Question: How Does Our Brain Process Positive and Negative Cues Associated with Thermosensation?
JG Grajales-Reyes, B Chen, D Meseguer… - …, 2024 - journals.physiology.org
Whether it is the dramatic suffocating sensation from a heat wave in the summer or the
positive reinforcement arising from a hot drink on a cold day; we can certainly agree that our …
positive reinforcement arising from a hot drink on a cold day; we can certainly agree that our …
GABA release from central amygdala neurotensin neurons differentially modulates ethanol consumption in male and female mice
GB Gereau, ML Torruella-Suárez, SE Sizer… - …, 2024 - nature.com
The central nucleus of the amygdala is known to play key roles in alcohol use and affect.
Neurotensin neurons in the central nucleus of the amygdala have been shown to regulate …
Neurotensin neurons in the central nucleus of the amygdala have been shown to regulate …
[HTML][HTML] GABA Release From Central Amygdala Neurotensin Neurons Differentially Modulates Reward and Consummatory Behavior in Male and Female Mice
The central nucleus of the amygdala is known to play key roles in alcohol use and affect.
Neurotensin neurons in the central nucleus of the amygdala have been shown to regulate …
Neurotensin neurons in the central nucleus of the amygdala have been shown to regulate …
[HTML][HTML] Distinct eLPBChAT projections for methamphetamine withdrawal anxiety and primed reinstatement of conditioned place preference
W Chen, H Guo, N Zhou, Y Mai, T Hu, X Xu, T He… - Theranostics, 2024 - ncbi.nlm.nih.gov
Methamphetamine (METH) withdrawal anxiety symptom and relapse have been significant
challenges for clinical practice, however, the underlying neuronal basis remains unclear …
challenges for clinical practice, however, the underlying neuronal basis remains unclear …
General Anesthesia Activates a Central Anxiolytic Center in the BNST
D Lu, S Choi, J Park, J Kim, S Zhao… - bioRxiv, 2023 - biorxiv.org
Low doses of general anesthetics like ketamine and dexmedetomidine have anxiolytic
properties independent of their sedative effects. How these different drugs exert these …
properties independent of their sedative effects. How these different drugs exert these …
Divergent changes in PBN excitability in a mouse model of neuropathic pain
ML Torruella-Suárez, B Neugebauer, K Flores-Felix… - Eneuro, 2024 - eneuro.org
The transition from acute to chronic pain involves maladaptive plasticity in central
nociceptive pathways. Growing evidence suggests that changes within the parabrachial …
nociceptive pathways. Growing evidence suggests that changes within the parabrachial …
The spino-parabrachio-amygdaloid pathway is critical for the manifestation of chronic pain
Pain is a complex phenomenon that elicits somatosensory and motor reflexive responses
alongside enduring emotional and autonomic changes. Although pain serves as a protective …
alongside enduring emotional and autonomic changes. Although pain serves as a protective …
Converging inputs compete at the lateral parabrachial nuclei to dictate the affective-motivational responses to cold pain
P Reddy, S Chaterji, A Varughese, A Sathyamurthy… - bioRxiv, 2024 - biorxiv.org
The neural mechanisms of the affective-motivational symptoms of chronic pain are poorly
understood. In chronic pain, our innate coping mechanisms fail to provide relief leading to …
understood. In chronic pain, our innate coping mechanisms fail to provide relief leading to …
Tac1-expressing neurons in the central amygdala predominantly mediate histamine-induced itch by receiving inputs from parabrachial Tac1-expressing neurons
YN Zhang, SJ Shi, E Mao, X Wang, YH Zhou, YL Chen… - 2024 - researchsquare.com
Itch is a distinct and bothersome sensation closely associated with a strong urge to scratch.
Both the parabrachial nucleus (PBN) and the central amygdala (CeA) are responsive to itch …
Both the parabrachial nucleus (PBN) and the central amygdala (CeA) are responsive to itch …