Background Mild cognitive impairment (MCI) is the preclinical and transitional stage
between healthy ageing and dementia that may be a potential 'target'for interventions …

An estimated 47 million people worldwide are living with dementia in 2015, and this number
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …

Abstract The Alzheimer's Disease Assessment Scale–Cognitive Subscale (ADAS-Cog) was
developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer's disease …

Abstract “The Scaffolding Theory of Aging and Cognition (STAC)”, proposed in 2009, is a
conceptual model of cognitive aging that integrated evidence from structural and functional …

Background By 2050, it has been estimated that approximately one-fifth of the population
will be made up of older adults (aged≥ 60 years). Old age often comes with cognitive …

Background Maintaining cognitive function is an important aspect of healthy ageing. In this
study, we examined age trajectories of cognitive decline in a large nationally representative …

Background Whether hearing loss is independently associated with accelerated cognitive
decline in older adults is unknown. Methods We studied 1984 older adults (mean age, 77.4 …

Hearing loss is associated with poor cognitive performance and incident dementia and may
contribute to cognitive decline. Treating hearing loss with hearing aids may ameliorate …

Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …

Purpose We aimed to quantify the relative risk of progression from mild cognitive impairment
(MCI) to dementia in people with and without diabetes, and with and without the MetS …