SARS‐CoV‐2 and its variants of concern including Omicron: a never ending pandemic
RK Mohapatra, S Kuppili… - Chemical Biology & …, 2022 - Wiley Online Library
The ongoing COVID‐19 pandemic caused by SARS‐CoV‐2 is associated with high
morbidity and mortality. This zoonotic virus has emerged in Wuhan of China in December …
morbidity and mortality. This zoonotic virus has emerged in Wuhan of China in December …
SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters
F Armando, G Beythien, FK Kaiser, L Allnoch… - Nature …, 2022 - nature.com
Since its discovery in 2019, multiple variants of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) have been identified. This study investigates virus spread and …
coronavirus-2 (SARS-CoV-2) have been identified. This study investigates virus spread and …
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes several proteins
that inhibit host interferon responses. Among these, ORF6 antagonizes interferon signaling …
that inhibit host interferon responses. Among these, ORF6 antagonizes interferon signaling …
COVID-19 and multiple sclerosis: a complex relationship possibly aggravated by low vitamin D levels
WD Fernandes de Souza, DM Fonseca, A Sartori - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an exceptionally
transmissible and pathogenic coronavirus that appeared at the end of 2019 and triggered a …
transmissible and pathogenic coronavirus that appeared at the end of 2019 and triggered a …
SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model
SARS-CoV-2 variants of concern (VOC) have triggered infection waves. Oral antivirals such
as molnupiravir promise to improve disease management, but efficacy against VOC delta …
as molnupiravir promise to improve disease management, but efficacy against VOC delta …
In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting
WJ Tu, M Melino, J Dunn, RD McCuaig… - Nature …, 2023 - nature.com
In vitro, ACE2 translocates to the nucleus to induce SARS-CoV-2 replication. Here, using
digital spatial profiling of lung tissues from SARS-CoV-2-infected golden Syrian hamsters …
digital spatial profiling of lung tissues from SARS-CoV-2-infected golden Syrian hamsters …
Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics
For coronavirus disease 2019 (COVID-19), effective and well-understood treatment options
are still scarce. Since vaccine efficacy is challenged by novel variants, short-lasting …
are still scarce. Since vaccine efficacy is challenged by novel variants, short-lasting …
Vitamin D and the Ability to Produce 1,25(OH)2D Are Critical for Protection from Viral Infection of the Lungs
Vitamin D supplementation is linked to improved outcomes from respiratory virus infection,
and the COVID-19 pandemic renewed interest in understanding the potential role of vitamin …
and the COVID-19 pandemic renewed interest in understanding the potential role of vitamin …
Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning
GR Meehan, V Herder, J Allan, X Huang, K Kerr… - PLoS …, 2023 - journals.plos.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has continued to evolve
throughout the coronavirus disease-19 (COVID-19) pandemic, giving rise to multiple …
throughout the coronavirus disease-19 (COVID-19) pandemic, giving rise to multiple …
Intranasal or airborne transmission-mediated delivery of an attenuated SARS-CoV-2 protects Syrian hamsters against new variants
CB Stauft, P Selvaraj, F D'Agnillo, CA Meseda… - Nature …, 2023 - nature.com
Detection of secretory antibodies in the airway is highly desirable when evaluating mucosal
protection by vaccines against a respiratory virus, such as the severe acute respiratory …
protection by vaccines against a respiratory virus, such as the severe acute respiratory …